West Resp Physio 9th Ed

Question 1

Smallest airways without alveoli

Answer 1

Terminal bronchioles

Question 2

Average volume of anatomic dead space

Answer 2

150 mL

Question 3

On average erythrocytes spend how much time in pulmonary capillary network?

Answer 3

0.75 seconds

Question 4

Volume of respiratory zone of lung

Answer 4

2.5-3 liters

Question 5

Methods of measuring total lung capacity, FRC or residual volume

Answer 5

Helium dilution technique, helium is insoluble in blood. Body plethysmograph.

Question 6

Equation for measuring FRC with helium dilution technique

Answer 6

C1V1 = C2(V1+V2), solve for V2

Question 7

Diffusion described by Fick’s Law

Answer 7

Diffusion ~ D * (P1-P2) * A/T
D diffusion constant
P1 partial pressure
P2 partial pressure
A area
T thickness

Question 8

Area of blood gas barrier in lungs

Answer 8

50-100 square meters

Question 9

Thickness of blood gas barrier in lung

Answer 9

0.3 micrometers

Question 10

Normal value of diffusing capacity for carbon monoxide at rest

Answer 10

25 mL/min/mmHg, increases 2-3 times with exercise

Question 11

How much faster is CO2 diffusion through tissue than O2?

Answer 11

20 times because of higher solubility

Question 12

Diffusion constant is proportional to

Answer 12

Solubility of gas

Question 13

Diffusion constant is inversely proportional to

Answer 13

Square root of molecular weight of gas

Question 14

Equation for diffusing capacity of lung for carbon monoxide

Answer 14

DL = VCO / PACO
VCO volume of carbon monoxide
PACO alveolar partial pressure of carbon monoxide

Question 15

Four causes of hypoxemia

Answer 15

Hypoventilation
Shunt
V/Q mismatch
Diffusion limitation

Question 16

Normal pH of CSF

Answer 16

7.32

Question 17

Ventilation increases by how liters per minute for each 1 mmHg rise in PCO2

Answer 17

2-3 liters per minute