weight loss

Question 1

weight loss drugs

Answer 1

Orlistat (Rx: Xenical, Ali-OTC)
Qysmia: Phentermine +topiram
Contrave: Naltrexone+ Buprop
Saxenda: Lirgaglutide
Wegovy: semaglutide

Question 2

phentermine

Answer 2

LOMAIRA
C-IV
- simulant and Inc NE
- CI: MAOI ( hypertensive crisi)
- lomaira tid before meals

Question 3

Orlistat

Answer 3

Xenica, Alli
- Pancreatic lipase inhibitor
- Binds to fat and dec fat absorption
- take with or upto 1hr after meal
- malasborption of fat soluble vitamins (Vit A, D,E, K)
- Pregnancy cat X

Question 4

Qysmia

Answer 4

Phentermine+ Topiramate
- QD

SE:
- Insomnia,
- kidney stone– Inc fluid intake
- anticholinergic
- Do not give in preg - topiramate birth def
- Topiramate cause hyperthermia ( does not allow to sweat)

Topiramate indic: migraine, seizure
- cause kidney stone, hyperthermia

Question 5

Contrave

Answer 5

Naltrexone+ Bupropion
(opioid antagoist +antidepressant)
- titrate due to nausea
- Uncontrolled HTNBup Inc DO & NE
- seizure disorder from Buprop
- Don’t use if pt on opioid
- dont use during or within 14 days MAOI

BUPropion: iNc DO and NE, cause seizure

Question 6

Liraglutide

Answer 6

Saxenda
- GLP-1 agonist
- dose : 3mg subq

Side Effect
G: gall bladder dx, gastroporesis
L: Wt loss
P: Pancreatitis
T: thyroid tumors

can caus hypoglycemia when comb wiht insulin

Question 7

semaglutide

Answer 7

Wegovy
- GLP 1 agonist
- dose: 2.4mg once weekly

Question 8

solriamfetol

Answer 8

sunosi (C-IV)
- for Narcolepsy

Question 9

Pitolisant

Answer 9

wakix
- Narcolepsy