Weekly Quiz Questions Flashcards
Dimorphic fungi demonstrate yeast and mold at what temperatures?
Yeast - 37 degrees
Mold - 25 degrees
The most common means of acquiring a fungal infection
inhalation of spores
Aseptate
without cross walls
Hyphae
tubular structures comprising mold, form of fungal growth
Mycelium
network of hyphae
Spore
Reproductive structure
Superficial infection
Outermost dead layer of the skin or hair
Subcutaneous infection
*** deeper skin layers, including muscle, bone, connective tissue
Systemic infection
internal organs or deep tissues of the body
Cutaneous infection
Polyenes
binds to ergosterol, create ion channels that disrupts the cell membrane
Azoles
Inhibits/disrupts cell membrane synthesis
Echinocandins
inhibits/disrupts cell wall synthesis
Flucytosine
interferes with synthesis of DNA, RNA and proteins
Dimorphic fungus
Primary vs Opportunistic pathogen
Blastomyces dermatitis
large, spherical, thick walled yeast cells 8-15um in diameter, usually with a single bud that is connected to the parent by a broad base
Immunocompromise patients, particularly those who have uncontrolled diabetes mellitus and those who are receiving prolonged corticosteroid, antibiotic, or cytotoxic therapy, are at the greatest risk of developing infection with ?
Mucurmycetes
Prevention measures for candidemia
Host conditions that are associated with an infection incidence of Candida albicans infections include
Diabetes
prolonged antibiotic use
pregnancy