week two study tips Flashcards

1
Q

how do plants make carbs?

A

green plants use energy from the sun, carbon dioxide and water to create glucose (simple carb) and oxygen, glucose is stored or metabolized to form starch and fiber (complex carbs).

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

what is a monosaccharide? name the 3 monosaccharides and their major characteristics.

A

glucose: major mono, part of every di and polysach, aka dextrose, called blood sugar, energy for cells (esp, brain, nervous system, RBC), main source = breakdown of starches and sucrose fructose: sweetest, in sucrose (table sugar), fruit, honey, HFCS, converted to glucose in liver galactose: found in lactose, sugar in milk, converted to glucose in liver

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

what are the steps to carbohydrate conversion to glucose

A

.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

what are the 3 names of disaccharides and a major source for each?

A

disacs are simple sugars: sucrose (gluc + fruc): sugar–sugar can, sugar beets, honey, maple sugar lactose (gala+gluc): milk products maltose (gluc + gluc): digestion of starch, barley, role in fermentation and alcohol production

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

what are the 3 types of polysacs. how are they digested? what are their purposes?

A

starches (amylose, amylopectin): digestible, made in plants dietary fiber: indigestible, fermented in colon glycogen: storage from of glucose

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

as you may know, enzymes work on glucose molecules at then ends of each branch. which starch is metabolized more quickly and what effect will this have on blood glucose?

A

.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

what is the importance of glycogen being more highly branched in regards to metabolism?

A

.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

why is it important to break down glycogen stores quickly?

A

.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

when do you use glucose from glycogen stores as opposed to from food you just consumed?

A

.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

what if you run out of glycogen? will fat convert to glucose? will the body break down protein for conversion to glucose?

A

.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

with limited storage capacity of glucose as glycogen, what happens to excess glucose consumed?

A

.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

why can’t cellulose and other plant materials be digested? what are some examples of starch and cellulose?

A

the body cannot break down the bonds (the beta linkages between cellulose are not digestible and must past through GI tract)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

what is the difference between soluble and insoluble fiber?

A

insoluble fiber comes from unrefined whole grains, wheat, rye, rice, and vegetables. its forms are cellulose, hemicellulose, and lignin. and it non-fermentable by the bacteria in the colon and does not dissolve in water. it adds to ‘roughage’ or fecal bulk and decreases intestinal transit time (ya poop faster). soluble fiber comes from fruit, vegetables, rice bran, psyllium seed, barley, oats, and beans. its forms are gum, pectin, and mucilage. it is a viscous fiber that swells and dissolves in water and can be fermented in the colon, providing energy to that area. it delays gastric emptying, results in a slow and steady glucose absorption, and binds (lowers) cholesterol.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

how can fiber help with: constipation, hemorrhoids, and diverticula? which is most helpful in each situation?

A

constipation: soluble fiber; can be broken down, fermented, and dissolved hemorrhoids: soluble, for similar reasons listed above. an non-stressed bowel movement is needed diverticula:

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

how can fiber help in blood glucose control?

A

soluble fiber slows glucose absorption, decreasing insulin production and increasing satiety, resulting in better blood glucose regulation*

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

study the 2nd slide on page 27 of chapter 4 lecture

A
17
Q

what is the RDA and AMDR for carbs?

A

RDA: 130 grams/day for adults.

Recommendations vary for the AMDR: FNB: 45-65% of total calories

18
Q

what are the AAND fiber recommendations?

A

20-35g/day

19
Q

how does lactose maldigestions differ from lactose intolerance? how can one manage them?

A

.

20
Q

what is gluconeogenesis and when does it happen? when would a body be in ketosis?

A

gluconeogenesis is when glucose is made from protein because carbs are in short supply. a body is in ketosis when fat is used for energy and the fat breakdown is incomplete, resulting in ketones, which are acidic

21
Q

what are normal glucose levels? what is hyperglycemia? hypoglycemia?

A

healthy ranges: fasting: 70-100mg/dl; post prandial (2hrs after a meal): <140mg/dl

hyper: high blood sugar levels
hypo: low blood sugar levels

22
Q

how do hormonoes impact glucose control?

A

the pancreas releases insulic and glucagon.

-insulin is secreted after the meal. it:

  • increases glucose uptake by cells
  • promotes glycogen synthesis
  • reduces gluconeogensis
  • net effect: lowers BG

-glucagon is secreted when blood glucose gets low

  • summons glucose from storage (glycogen)
  • enhances gluconeogensis
  • net effect: raises BG

-epinephrine

  • ‘fight or flight;’ summons glucose quickly when stressed
  • breaks down glycogen
  • net effect: raises BG
23
Q

fill in the blanks:

  1. elevated blood _________
  2. _________ releases insulin
  3. _________ transported into cells
  4. conversion of _________ into _________
  5. normalization of _________
  6. low blood _________
  7. pancreas releases _________
  8. _________ gluconeogensis
  9. breakdown of _________ to _________
  10. normalization of _________
A
  1. glucose
  2. pancreas
  3. glucose
  4. glucose; glycogen
  5. blood glucose
  6. glucose
  7. glucagon
  8. increased
  9. glycogen; glucose
  10. blood glucose
24
Q

what causes type 1 diabetes mellitus? type 2? gestational diabetes? how is this group of disorders characterized?

A
  • type 1 caused by the pancreas not secreting insulin, resulting in glucose buildup in blood and the liver producing glucose, exarcerbating hyperglycemia, resultiing in fat breaking down ketoacidosis and development of acetone breath. body attacks pancreas and renders beta cells useless
  • type 2 caused by abnomrla responses to insulin by muscle, adipose, and liver cells (insulin resistance, resulting in glucose being unable to enter the cell and the liver producing more glucose (gluconeogenesis). pancreas overexerts itself due to insulin resistance over time and cells that are normal responsive to insulin become resistant to its effects

characterized by: elevated blood glucose concentrations, disordered insulin metabolism, inability to secrete sufficient insulic/use insulin effectively

25
Q

what are the symptoms of diabetes? and why do they occur?

A
  • frequent urination
  • dehyrdation and dry mouth, increased thirst
  • blurred vision
  • increased infections
  • weight loss
  • increased hunger
  • fatigue
26
Q

what is the definition of metabolic syndrome?

A

*

27
Q

what is a coenzyme and how does it function in our bodies?

A

* (see animation on carmen)

coenzymes aid in the function of various enzymes. without the coenzyme, the enzyme cannot function, and deficiency symptoms associated with the missing vitamin eventually appear.

28
Q

how can vitamins be lost/destroyed? how can we best preserve vitamin content of food?

A

improper storage or excessive cooking can destroy water soluble vitamins. (heat, light, air, cooking in water, alkalinity)

we can best preserve vitamin content by eating foods soon after harvest, eating frozen foods if fresh is unavailable, freezing foods not conumed in a few days, and not blacning foods

29
Q

what is the enrichment act and why was it enacted?

A

*

30
Q

what are main functions, sources, deficiency symptoms/diseases, and toxicity symptoms/diseases for thiamin (vitamin b1)

A
  • functions
    • releases energy from carbs
    • important for ATP producing energy pathways
    • chemical reactions that make RNA, DNA, neurotransmitters
  • deficiency
    • beriberi (i cant i cant)
      • weakness, loss of appetite, irritability, nervous tingling, poor arm and leg coordination, calve pain
      • seen in areas where polished white rice is a staple
      • glucose can’t be metabolized to release energy because of lack of thiamin
      • alcoholism increases deficiency risk
  • major sources: pork, whole grains, breakfast cereals, enriched grains & flour
  • average intakes meet RDA
31
Q

what are main functions, sources, deficiency symptoms/diseases, and toxicity symptoms/diseases for riboflavin (b2)?

A
  • functions
    • coenzyme particpates in energy0yielding pathways
    • metabolism of some vitamins and minerals require it
    • antioxidant role through support of glutathione and peroxidase
  • deficiency
    • inflammationo f mouth and tongue, dermatitis, cheilosis, eye disorders, sensitivity to sun, confusion. occurs after 2 mos.
  • found in grains, dairy, and protein groups. a vampire, i.e. destroyed by light
32
Q

what are main functions, sources, deficiency symptoms/diseases, and toxicity symptoms/diseases of niacin (b3)?

A
  • functions
    • coenzyme forms function in many cellular emtabolic pathways and over 200 enzymatic reactions
    • in body as nicotinic acid and nicotinamide
  • deficiency
    • pellagra: dementia, diarrhea, dermatits and possibly leading to death
    • dementia: loss or decrease in mental function
    • reached epidemic proportions in southeastern US because niacin in corn can’t be absorbed
  • intakes are ~2x RDA. best food sources in protein group and little lost in cooking.
  • UL pertains only to nicotinic acid (supplement) resulting in: headache, itching, increased blood flow to skin, seen when intakes are above 100mg/day
33
Q

what are main functions, sources, deficiency symptoms/diseases, and toxicity symptoms/diseases of vitamin b6?

A
  • functions
    • coenzymes needed for carbohydrate, protein and lipid metabolism
    • 100 chemical reactions that involve metabolism of amino acids adn protein
    • synthesis of neurotransmitters, conversion of tryptophan to niacin, breakdown of stored glycogen, synthesis of hemoglobin and white blood cells
  • deficiency
    • widespread symtopms: depression, vomiting, skin disorders, irritation of the nerves, anemia, imparied immune response
    • alcoholics susceptible
  • major sources are animal products and RTE breakfast cereals, as well as protein group
  • can be easily destroyed by heating and freezing
  • UL 100 milligrams
    • 2-6g/day 2mo+ results in irreversible nerve damage
    • walking difficulties, hand and foot tingling, numbness
34
Q

what are main functions, sources, deficiency symptoms/diseases, and toxicity symptoms/diseases of pantothenic (b5) and biotin (b7)?

A
  • function
    • pantothenic
      • required for synthesis of coenzyme a, allowing for release of energy from carbs, lipids, and protein
      • widespread in food, deficiency unlikely
    • biotin
      • widespread symptoms of deficiency
      • foods rich in protein are sources, like egg yolks, peanuts, cheese
      • synthesized by intestinal bacteria
      • deficiency unlikely
      • in raw egg white, bound to avidin and absorption inhibited
      • no ul set
35
Q

what are main functions, sources, deficiency symptoms/diseases, and toxicity symptoms/diseases of folate (b9)?

A
  • function
    • coenzymes help form DNA and metabolize amino acids
    • formation of neurotransmitters in brain
  • deficiency
    • immature cells can’t divide in early phases of RBC synthesis
      • can’t form new DNAm results in megaloblasts or a giant immature RBC
    • symptoms: inflammation of tongue, diarrhea, poor growth, mental confusion, depression, nerve function problems
    • maternal folate deficiency may result in: neural tube defects, spina bifida (improper closer of neural tube, anencephaly (absence of some/all of brain+skull)
  • major sources: green, leafy veggies as well as other vegetable, oj, dried beans, organ meats, RTE cereals, bread, and milk. susceptible to destruction by heat and oxygen
  • RDA: 400micrograms DV: same
  • UL: 1000 micrograms (synthetic)
    • large doses can mask signs of b12 deficiency
36
Q

what are main functions, sources, deficiency symptoms/diseases, and toxicity symptoms/diseases of vitamin b12 (cobalamin or cyanocobalamin)?

A
  • requirements
    • requires a protien from salivary gland and stomach acid
    • absorption requires intrinsic factor: a protein like compound produced by the stomach that enhances vitaminb12 absorption in the ileum
  • functions
    • folate metabolism
      • b12 required to convert folate coenzymes to the active forms needed
    • maintains myelin sheath
  • deficiency
    • irregular muscular actions, impaired reflxes, paralysis, possibly death
    • pernicious anemia: macrocytic anemia + associated nerve degeneration resulting in paralysis and death
      • ususally caused by autoimmue disease that destroys the stomach cells that produce stomach acid
    • inadequate intake rare: susceptible: vegans, infants breastfed by vegetarians
  • major sources: organ meats, seafood, RTE cereals, milks, eggs
37
Q

what are main functions, sources, deficiency symptoms/diseases, and toxicity symptoms/diseases of vitamin c?

A
  • functions
    • collagen formation
    • formation of other compounds like carnitine, serotonin and norepinephrine
    • antioxidant, can readily accept and donate electrons
    • absorption of iron
    • immune function
      • protect immune cells from being degraded by oxidant reactions
      • may reduce duration or severity of symptoms
  • deficiency
    • scurvy: bleeding gums, tooth loss, bruising and scaly skin
  • major sources: citrus fruits, strawberries, green peppers, cauliflower, broccoli, cabbage, papayas, romaine lettuce
    • brighter fruit or veggie = higher vitamic c content
    • rapidly lost in processing and cooking
  • excess consumption excreted by kidneys, decreasing absorption defiiciency
    • more than 2000mg/day may cause stomach inflammation and diarrhea
38
Q

what are main functions, sources, deficiency symptoms/diseases, and toxicity symptoms/diseases of choline and other vitamin like compounds?

A
  • function
    • cell membrane structure, precursor for several phospholipids
    • single-carbon metabolism: sytnhesis of neurotransmitters, modifications of DNA during embryonic development, metabolism of homocysteine
    • prevention of birth defects
    • part of acetylcholine
    • lipid transport
  • major sources: soybeans, egg yolks, beef, cauliflower, almonds, peanuts. can be synthesized in body
  • AI 550mg for men and 425 for women
  • UL at 3.5mg/day