Week Two Flashcards

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1
Q

What did the gene pool evolve from and what did humans develop?

A
  • Gene pool evolved from hunter-gatherer lifestyle; physical activity required for food procurement
  • Humans developed “thrifty genes” – genes that maximise metabolic efficiency
  • Little change in human gene pool over 10 000 years
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2
Q

What is thrifty storage?

A

Replenish skeletal muscle glucose and TG: more efficient storage of excess glucose and TG in adipose tissue.

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3
Q

What does more thrifty storage equal?

A

More likely to survive through the next famine/activity phase until next feast.

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4
Q

During a famine or activity what happens?

A

Decrease in glycogen and TG stores.

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5
Q

What occurs during the feast?

A

Intake of glucose and fat

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6
Q

What occurs in the stalling of a famine or activity?

A
  • No cycling of metabolic processes= fuel gets shunted into an even greater and unhealthy storage.
  • Feast= Unlimited food supply with no exercise
  • Thrifty storage exists but famine and physical activity are not utilised
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7
Q

What is the result of evolution on energy expenditure?

A

-Average energy expenditure of modern humans is 38% of H-G ancestors

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8
Q

How do you find out the current health status of the population?

A
-How do we find out? 
o	Large scale surveys 
-Phone surveys 
-Need to be quick 
-Need to be easy for the participant to answer
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9
Q

What are METs?

A
  • Another method to estimate intensity

- MET’s (metabolic equivalent) denotes the energy required to complete a task/activity

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10
Q

What do we need to perform activity and what does 1 MET equal?

A

-We need O2 to perform activity, thus measuring oxygen consumption is the gold standard for measuring energy expenditure
o 1 MET = 3.5 ml/kg/min-1
-Ainsworth et al. (2000) has calculated the MET’S associated with a variety of different activities:
EXAMPLE
-Boxing in a ring (77 kg) = 17.1 METS
-Axe chopping (77 kg) = 22.9 METS
-Playing a Flute (77 kg) = 2.7 METS

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11
Q

What is the purpose of surveys in Australia?

A

-To inform Australia’s decisions by providing objective, trusted and relevant data and statistics on a range of matters including economic, social and population.

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12
Q

What is the World Health Organisation?

A
  • “Direct and coordinate international health within the united nations system” (WHO website)
  • Provide global statistics
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13
Q

What is the global inactivity percentages and where is it most prevalent?

A

-2008 – 31% of adults ≥ 15 were inactive
o Females = 34%
o Males = 28%
o Highest in Americas and Eastern Mediterranean
o Lowest in South East Asia

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14
Q

In the National Health Survey what was the percentage of inactivity, insufficiently active and what is recommended?

A
  • Recommended Level of PA = 55.5%
  • Insufficiently Active: 30%
  • Inactive: 15%
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15
Q

In the Australian Health Survey what were the results?

A
  • 1/3 of children and 1/10 young people did the recommended 60 minutes of activity per day
  • 60% of adults did less than recommended
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16
Q

What is inactivity?

A

-Not meeting the current recommendations for physical activity
o Less that 30 minutes of moderate intensity physical activity on most days of the week (< 150 min/week)

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17
Q

Why are people inactive?

A

-Why?
o Decrease in the amount of leisure time physical activity
o Increase in sedentary time in occupational and domestic duties

18
Q

What is the Health Burdon of Inactivity?

A

-Chronic inactivity is physiologically abnormal
o Human bodies fail to function properly to maintain health in many different ways when there is a loss of adequate amounts (historically ‘‘normal’’ amounts) of physical activity

19
Q

Define morbidity, mortality, all cause mortality and disease.

A
  • Morbidity – a diseased state, the existence of disease
  • Mortality – subject to death
  • All-cause mortality – all deaths that occur in a population
  • Disease – a disorder of structure or function in a human that produces specific symptoms
20
Q

Define chronic disease and non communicable disease.

A

-Chronic disease – a disease that persists for some time or has long lasting effects (more than three months)
o E.g. asthma, cancer, diabetes, arthritis, HIV/AIDS, multiple sclerosis
-Non communicable disease – condition or disease that is not caused by infectious agents (non transmissible).
o Can be chronic
-E.g. Chronic kidney disease, diabetes, asthma, Alzheimer’s

21
Q

What is the global burdon of inactivity?

A
  • Inactivity attributed to 3.2 million deaths in 2008
  • Physical inactivity = 4th cause of death due to non-communicable disease = 3 million (6%) preventable deaths every year
22
Q

How is burdon measured and what is it calculated as?

A

-For the individual:
o Morbidity and mortality are measured using the Disability-Adjusted Life Year (DALY)
-One DALY is a lost year of ‘healthy’ life
o DALY = YLL + YLD
o YLL = Years of Life Lost
o YLD = Years Lived with Disability
-Calculated as a combination of years of life lost due to premature mortality and equivalent ‘healthy’ years of life lost due to disability (morbidity)

23
Q

For society what is the economic burdon of inactivity?

A

-Economic burden – Cost $$$$
o Direct costs – associated with utilisation of healthcare resources, largest component is the cost of hospital admissions
o Indirect costs – premature retirement, absenteeism, carer costs

24
Q

What are Co-Morbidities of Inactivity?

A

-Modifiable risk factor for mortality and chronic disease
o Physical fitness vs physical activity= strong relationship with health outcomes
o Steeper for physical fitness

25
Q

What is Epidemiology?

A
  • Study of the distribution and determinants of disease or injury
  • Physical activity epidemiologists – interest in effect of physical inactivity on disease and injury
26
Q

What is Cardiovascular Disease, what are the most common and what is the main cause?

A

-Term used for conditions of the heart and/or vessels
-Most common:
o Coronary heart disease (CHD)
o Stroke
o Heart Failure
-Main cause of CVD is the process of atherosclerosis

27
Q

What are the Demographic and hereditary factors of cardiovascular disease?

A
  • age
  • sex
  • family history of CVD disease
28
Q

What are the behavioural factors of cardiovascular disease?

A
  • tobacco smoking
  • physical inactivity
  • poor nutrition (diet high in saturated fats)
  • high consumption of alcohol
29
Q

What are the Physiological risk factors of cardiovascular disease?

A
-Physiological risk factors 
o	high blood pressure/ hypertension 
o	high blood cholesterol / blood lipids 
o	overweight and obesity 
o	diabetes mellitus
30
Q

What is the prevalence of cardiovascular disease in Australia?

A
  • 2011-2012 = 22% had CVD
  • Attributable to 30% of 2012 deaths
  • 11% of hospitalisations
31
Q

What is Type 1 Diabetes?

A

-Catabolic disorder
-Lack of insulin thus glucose cannot be internalised
= starvation and the b/d of other tissues

32
Q

What is Type 2 Diabetes?

A
-Resistance to Insulin 
Modifiable risk factors: 
-Overweight and obesity 
-Lack of exercise 
-Poor Diet
33
Q

What are diabetes related complications?

A
o	Ketoacidosis 
o	Hyperglycaemia 
o	Hypoglycaemia 
o	Vascular damage 
-Eyes 
-Kidneys 
o	Neurological damage
- Foot Ulcers
34
Q

What are the statistics of Diabetes in Australia and globally?

A

-Fastest growing chronic condition in the world
-1.1 million Australians diagnosed with diabetes
o 10% Type 1 Diabetes
o 90% Type 2 Diabetes
-11% of total world healthcare spending
-5.1 million worldwide deaths in 2013 related to diabetes

35
Q

What is the prevalence of cancer globally?

A

-2008 – 13% of deaths can be attributed to cancer
-Smoking is the biggest preventable cause of cancer
-> 30% of cancer could be prevented
o Smoking
o Physical Activity
o Healthy Diet

36
Q

What is the prevalence of cancer in Australia?

A

-30% of all deaths

37
Q

What does inactivity increase the risk of?

A
o	Colon and rectum 
o	Breast 
o	Endometrium 
o	Gallbladder 
o	Kidney 
o	Oesophagus 
o	Ovary 
o	Pancreas
38
Q

What can physical activity reduce the risk of?

A
-Convincing evidence that physical activity can reduce the risk of: 
o	Colon 
o	Breast 
o	Prostate 
o	Lung 
o	Endometrial
39
Q

How are chronic diseases characterised?

A

-Many chronic diseases are characterised by “unpleasant” symptoms that will increase with physical activity

40
Q

What does pre-screening prevent?

A

-Exercise does present risks
o Musculoskeletal, CV, respiratory etc
-We want as many people who are capable to participate

41
Q

What is the purpose of pre-screening?

A
  • Pre-screening purpose is to identify people:
    1. With medical contradictions to exercise
    2. Signs and symptoms of clinical disease
    3. Risk factors that need consideration when exercising
    4. With special needs
42
Q

What are the various models of risk stratification?

A

-Ascertain an individual’s level of risk of experiencing an adverse event during physical activity
-Various models of risk stratification
o Vary from “are you ok to exercise” to ECG stress testing
-No guidelines for exercise testing and participation can cover all situations. Individual discretion is always required!