Week three- Acid-base balance Flashcards
What are the features of salts?
- Ionic bonds
- Structural components
- Electrolyte properties
What are the electrolyte properties?
Can conduct electricity due to the mobility of the positive and negative ions.
What are the features of acids and bases?
Covalent bonds
Metabolic control
Homeostasis
What do salts, acids and bases have in common?
Dissociate in water
Damaging in high concentrations
Do acids donate or accept protons?
accept
What do acids do when the dissociate in water?
Release a hydrogen ion (H+)
Do bases donate or accept protons?
Accept
What do bases do when the dissociate in water?
Release OH-
What is concentration measured in?
Moles per litre
mmol/L
What is pH measuring?
The acidity or alkalinity of a solution
Why does pH have to be a certain level?
Because some chemical processes only occur at specific pH.
Why is a change in pH important?
Allow mechanisms to activate enzymes
What happens in extreme pH changes?
Damage protein structures
What are the features of strong acids?
Dissociate completely
Irreversible
What are the features of weak acids?
Reach equilibrium
Reversible and concentration driven
What does the body’s basic pH lie between?
7.35 and 7.45
Why is some fluctuation of pH in blood necessary?
For normal bodily functions
What happens if there is an increase in H+ concentration?
Acidosis occurs (arterial blood pH is less than 7.35)
What happens if there is a decrease in H+ concentration?
Alkalosis occurs (arterial blood pH is above 7.45)
What are the three mechanisms that regulate pH?
- Chemical buffering
- Pulmonary ventilation (breathing)
- Renal function (kidney)
What is the main chemical buffering chemical in the blood?
Bicarbonate
What does the kidney excrete to help regenerate the HCO3-
H+
What do small increase in PCO2 in inspired air trigger?
Large increases in ventilation
What is the aim of buffering?
Moderate drasric changes in pH
What does cellular respiration produce?
H+
What does renal buffering do?
Excretes H+
restores bicarbonate to circulation
What is one of the factors that regulates ventilation?
Plasma pH