Week Eleven Quiz Flashcards
Infection
Caused by microorganisms and results in infection.
*not all inflammations are caused by infections
Two phases of inflammation
- Vascular- 10-15 min after
* delayed phase- associated with vasodilation and increased capillary permeability
NSAIDS
Nonsteroidal Anti Inflammatory Drugs
-used to decrease inflammation and pain for patients who have some kind of arthritic condition
Salicylates
- derived from salicylic acid
- aspirin comes from this group
Aspirin
- anti inflammatory drug
- AR: GI bleeding, tinnitus, ulceration
- TE: reduce pain and inflammatory symptoms, decrease body temp, to inhibit platelet aggregation
Para-chlorobenzoic acid
-used for rheumatoid arthritis and osteoarthritis
Phenalacetic acid derivatives
-it’s analgesic and anti inflammatory effects are similar to those of aspirin, but has minimal antipyretic effect
Propionic acid derivatives
-aspirin like but have stronger effects and create less GI irritation
Fenamates
- includes potent NSAIDS used for acute and chronic arthritic conditions
- gastric irritation is a common side effect
Oxicams
-indicated for long term arthritic conditions
Ibuprofen
NSAID
- AR: GI bleeding
- TE: reduce inflammatory process, reduce pain, reduce fever
Selective COX-2 inhibitors
-inhibits COX-1 to protect stomach lining and promoted decreased clotting time
Celecoxib
- non steroidal anti inflammatory: COX-2 inhibitor
- AR: peripheral edema
- TE: treat osteoarthritis and rheumatoid arthritis
Inflammation
A response to tissue injury and infection
Allopurinol(Zyloprim)
- anti gout
- AR: cataracts, Bradycardia
- TE: to treat gout and hyperuricemia
Pain threshold
Reflects the level of stimulation needed to create a painful sensation
Pain tolerance
The amount of pain a person can endure without having it interfere with normal functioning
Nociceptors
Sensory pain receptors in the peripheral tissues
- mechanical
- thermal
- chemical
Acetaminophen
Analgesic
AR:oliguria
TE:decrease pain and fever
SE: an overdose can be extremely toxic to the liver
NSAIDS
- All have analgesic,antipyretic, and anti inflammatory effects
- common side effects of NSAIDS is gastric irritation
Aspirin and children
Children under age 12 should not use aspirin
-because of risk of Reye’s syndrome use Tylenol
Addiction
Defined as a psychological and physical dependence upon a substance beyond normal voluntary control
-usually after prolonged use of substance
Morphine
- potent opioid analgesic
- effective against acute pain, MI pain, cancer pain, and relieving severe pain
- can cause respiratory depression, orthographic hypotension
Morphine antidote
Naloxone(Narcan)