Brainscape's Knowledge GenomeTM

Browse over 1 million classes created by top students, professors, publishers, and experts.


See full index

Pharmacology > Quiz Eight #2 > Flashcards

Quiz Eight #2 Flashcards

1
Q

Disintegration

A

Breakdown into smaller particles

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

Absorption

A

Movement of drug particles from GI tract to body fluids through:

  • passive absorption
  • active absorption
  • pinocytosis
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

Lipid soluble

A

Pass rapidly through GI membrane and blood brain barrier

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

Water soluble

A

Require enzyme or protein to pass through membrane

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

Bioavailability

A

% of drug that the body can now use

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

Distribution

A

Drug becomes available to body fluid and tissues

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

Protein binding

A

Drug must go where protein is going
-portion of drug that is bound is inactive other portion is free

-drugs bound by protein are going to remain in system a little bit longer

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

Free drugs

A

What is available to go to site of action and do what it needs to do

-when free level drug decreases, protein bound drugs release some of drug into free until the drug is out of the system.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

Volume of drug distribution (Vd)

A

Amount of the drug in the body/plasma concentration

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

Liver

A

The main organ for metabolism

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

1/2 life

A

The time it takes one one half of drug concentration to be eliminated.

  • and then half of that and half of that until drug is gone
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

Excretion(elimination)

A 
Kidneys-Urine
Liver-bile
Intestines-feces
Lungs-Co2,H2O
Skin-sweat
Milk ducts-breast milk
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

Creatinine clearance

A

Difference between your urine and your blood creatinine levels

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

Pharmacodynamics

A

The study of drug concentrations and its effects of the body

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

Primary effect

A

The desired/wanted effect

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

Secondary effect

A

Side effect

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
17
Q

Dose response

A

Amount of drug needed for desired effect, one patient may need more of a drug than somebody else

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
18
Q

Maximal efficacy

A

Medication is no longer more effective even if given more

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
19
Q

Peak

A

Point where drug reaches maximal effect but is not toxic

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
20
Q

Duration

A

The time period in which the drug is effective while in the therapeutic range

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
21
Q

MEC

A

Minimum effective concentration

22
Q

MTC

A

Minimum toxic concentration

23
Q

Onset

A

the time required after administration of a drug for a response to be observed.

24
Q

Receptor theory

A

refers to the fact that drugs have an effect of receptor sites on the cell membrane in order to cause a reaction

25
Q

Agonist

A

Produces a response

26
Q

Antagonist

A

Blocks a response

27
Q

Strong agonist

A

Drug attaches to receptor site extremely well, causes a strong reaction

28
Q

Weak agonist

A

does fit but doesn’t have a very strong reaction

29
Q

Stimulation and depression category

A

Causes the organ system to speed up or slow down

30
Q

Therapeutic index

A

Difference between the effective dose at 50% and the lethal dose at 50%

31
Q

Therapeutic range(window)

A

The plasma level of a drug between the minimal effective concentration for obtaining the desired effect and minimal lethal concentration(lowest plasma concentration)

32
Q

Peak levels

A

Peak drug levels indicate the rate of absorption(highest plasma concentration of drug)

33
Q

Trough

A

Trough levels indicate the rate of elimination(lowest plasma concentration)

34
Q

Loading dose

A

Giving a higher amount/dose to get that therapeutic range jump started

35
Q

Side effects

A

Other effects the drug has, could be desirable or undesirable

36
Q

Adverse reactions

A

A reaction that could be a possibility but don’t always know who will have the reaction EX: anaphylaxis

37
Q

Placebo effect

A

Physiologic without receiving the drug revealing a psychological effect

38
Q

Tachyphylaxis

A

Very short reaction in drug

-rapid decrease in response

39
Q

Drug interactions

A

The reactions that drugs have with eachother

40
Q

Additive

A

If you take two drugs that can have the same effect

41
Q

Synergistic

A

While taking two drugs they multiply the effect

42
Q

Drug-food

A

Can either increase or decrease breakdown of certain drugs

43
Q

Drug-lab

A

Chemotherapy drugs can effect drugs more severely

44
Q

Phototoxicity

A

Immediate response of chemical reaction between drugs and light

45
Q

Pharmaceutic

A

Solid being desolved into liquid to be absorbed

46
Q

Category 1 drugs

A

Drugs judged to be both safe and effective

47
Q

Category 2

A

Drugs judged to be either unsafe or ineffective, these drugs should not be included in nonprescription products

48
Q

Category 3

A

Drugs for which there is insufficient data to judge safety and efficacy

49
Q

Five plus five rights of med administration

A 
Right assessment 
Right documentation 
Patients right to education 
Right evaluation
Patients right to refuse
50
Q

Pinocytosis

A

Cells Carey drug across membrane by engulfing the drug particles

Pharmacology (13 decks)

Brainscape helps you reach your goals faster, through stronger study habits.
© 2024 Bold Learning Solutions. Terms and Conditions