Week 8 - Renal Flashcards
the renal system consists of ? (4)
- kidneys
- ureter
- bladder
- urethra
the kidney functions?
primary function is to maintain a stable environment for optimal cell and tissue metabolism
- excrete metabolic wastes
- regulate blood Ph
- secretes hormones to regulate BP
Acute Kidney injury (Define)
sudden, severe impairment of renal function causing an acute build up of toxins in the blood
- results in fluid and electrolyte imbalances
- can develop over hours or days
AKI - Causes
- (3 main types)
Prerenal: (outside the kidneys)
*due to factors external to the kidneys that reduce renal blood flow
- hypovolaemia (dehydration, Hemorrhage, Diarrhoea and vomiting)
- decreased cardiac output
(shock, AMI, hypotension)
Intrarenal; (injury directly to the kidneys)
- Acute Tubular Necrosis
(can be caused by side effects of medications or triggered by acute events such as hypotension. results in death of the tissue within the tubule > causing blocking of the tubules and decrease in function over time)
Post Renal: (damage further down in the renal tract)
*involves mechanical obstruction of urinary outflow >
as flow of urine is obstructed urine refluxes into the renal pelvis which impairs renal function
- enlarged prostate
- renal cancer
- bladder cancer
AKI - Risk Factors
- pre existing renal impairment (diabities0
- hypotension
- dehydration
- age > 70
- admission to icu, AKI occurs in 20 - 50% of pts admitted to icu
specific conditions:
- burns
- cardiac disease
- sepsis/ MODS
- abdominal surgery
AKI - signs and symptoms (11)
- decreased urine output
- proteinuria
- volume overload
- hypotension (early)
- hypertension (late)
- arrhythmias
- PO
- pleural effusions
- nausea and vomiting
- anorexia
- seizures
AKI - pt assessment
- what to ask about when taking history?
- dysuria
- incontinence
- nocturia
- haematuria
- diabities
- hypertension
AKI - aim of treatment
maintain effective circulating volume
- treat cause!
AKI - pt assessment
- DRSABCD
Airway:
- patent?
- 80% of pts with AKI will require mechanical ventilation
Breathing:
- RR, WOB
- High flow 02
- observe for kussmauls respirations (Breathing rapidly and deeply) bodys attempt to get rid of C02
- auscultate lungs (crackles or diminished breath sounds)
Circulation
- HR
- BP (GFR cannot be maintined with systolic BP <9 intubate (indicate uremia very bad and requires urgent dialysis)
AKI - interventions & investigations
- IV access
- FBC
- IDC
- CVC
- (+/-) inotropes to maintain perfusion to the kidneys
- ECG (look for signs of hyperkalaemia)
- CXR
- abdominal xray
- CT
- pathology
hyperkalaemia on ECG
- prolonged PR interval
- wide QRS
- tall peaked T waves
- untreated can lead to VF and VT
how to treat hyperkalaemia?
insulin and glucose (10 - 20 units actrapid) > takes potassium with glucose into the cells > = decreased potassium
Dialysis - define
is the diffusion of solute molecules across a semi permable membrane from an area of higher concentration to lower concenctration
- used to remove excess fluid and metabolic waste products in the pt with renal failure
dialysis - 2 types
- haemodyalysis
- peritional dialysis
Haemodialysis
a procedure by which blood passes by an artificial semi permable membrane outside the body
- needs a permanent vascular access site > internal arteriovenous fistula