Week 8: Reflex control of circulation Flashcards
What results in the elimination of the sympathetic nerve activity?
drop in the mean aterial pressure
Sympathetic nerves innervate what elements of the cardiovascular system?
- blood vessels
- heart
Sympathetic nerves innervate which type of vessels?
- resistance vessels (arteries)
- capacitanec vessels (veins)
What innervation does the heart recieve?
- sympathetic (SA, AV node + cardiac muscle)
- parasympathetic ( only SA and AV nodes)
What is the pathway of the negative feedback regulation?
Setpoint → discriminator → forward signal → effector/s → regulated paramter → feedback signal
What are the three different types of receptors?
- high pressure receptors
- low pressure receptors
- chemoreceptors
What are the high pressure receptors and where are they located?
baroreceptors
located in the carotid sinus and in the aorta
Describe the baroreceptors in the carotid sinus
- predominantly elastic fibers (no collagen, no smooth muscle)
- sensitive to ↑ transmural pressure
- distention → stretch receptors
What is the graph displaying the relationship between arterial pressure and sinus nerve activity? What is significant?
The slope is largest at normal physiological range therefore the firing rate is very susceptible to change.
What is the major difference between the carotid baroreceptors and the aortic baroreceptors?
The dynamic range of the carotid baroreceptors is higher than the aoritc baroreceptors
Explain the graph displaying that the receptor potential ch changes in response to the elevation of arterial blood pressure
What are the receptor potential changes converted to?
action potential frequencies
Explain the graph
if the carotid is clamped the pressure in the carotid sinus is reduced due to the lack of blood flow
What is the graph representing the relationship between the isolated carotid sinus and systemic pressure?
Schematic scheme of the feed back regulation in response to ↑ mean arterial pressure
What is the response to sustained hyper tension in regards to the firing of the baroreceptors?