Week 8: AMLR Flashcards
what is the wave sequence of an AMLR waveform
- Na, Pa
* then Nb, Pb
Po waveform on AMLR
- a small positive wave before Pa
- –is thought by some to not be a true component of AMLR
- –maybe its pam?
the Pa waveform on AMLR
*a positive peak at about 30 ms after click stimulus
PAM and AMLR
- pam occurs within the same frequency region as AMLR
- –myogenic potentials 10-20 ms
- –can distort the AMLR in the 12-25 ms region (Na and Pa)
- –PAM can be mistaken for AMLR
- –can also distort ABR recordings
- need to relax neck and use lower stimulus levels to avoid pam artifact
neural generators of AMLR
- subcortical/thalamic generators (complex generators)
- –Na= thalamic MGB and IC
- –Pa=the association cortex?
- the lack or knowledge of the generators precluded the use of AMLR as a response index for threshold audiometry
AMLR protocol
- stimulus: click (2-1-2 TB for threshold)
- rate: 7.1/sec or 17/sec
- –slower like 1 or 2/sec for younger pts
- polarity: alternating
- intensity: same as for ABR
- sweeps: 1000
- presentation: monaural AC
- transducer: inserts
- masking” 70 dB when indicated
- amplification: 75000
- sensitivity: 50 micro volts
- window: 10-50 up to 80/100 ms
- filters: bandpass 10-1500 Hz
- electrodes:
- –threshold: Fz, A1, A2, Fpz
- –neurodiagnostics: C5 and C6
AMLR electrode montage
- noninverting electrode
- –for threshold finding:
- —–Cz= large Pa amplitude
- —–Fz= large amplitude
- –for otoneurologic (looking for asymmetry)
- —–C3 or C5= L temproparital
- —–C4 or C6= R temproparietal
when to do AMLR with a click vs a toneburst?
- clicks for otoneurologic purposes
- TB for thresholds
- –dont generally use AMLR for thresholds because they mature later, but when mature responses will be between 5-10 dB of threshold
AMLR with increase in intensity
*not much of a latency shift, but an increase in amplitude with increased intensity
stimulus rate for adults with AMLR
- recommended rate is 17/second
- –using a 50ms analysis window, the max allowable rate is 20.s so a stable AMLR will be present up to 15-16/s
- fast rates (15-40Hz)
- –using 40/s gives 40 Hz response= steady-state response
- —–overlapped response
- —–this is a sine wave
stimulus rate for newborns for AMLR
- lower rate: 1-2/s
- rate>/= 5/s would mean no Pa wave in newborns
- –note that with infants Na is greater than Pa which is the opposite of what you see with adults
stimulus polarity with AMLR
alternating is the best
age effect on AMLR
- AMLR can be elicited at any age, but varies
- –Pa amplitude increases from infancy to childhood, then decreases with advancing age
- AMLR are not adult-like until 8-10 yrs or later
- –at 8-10 yrs still need to be interpreted with caution
- need age-related norms
AMLR in adults vs neonates and young children
- adults
- –Pa is valid and reliable
- –ipsi and conta recording while stimulating one ear with a moderate intensity gives clear AMLR to be recorded from both sides of the head
- neonates and young children
- –Na is the most reliable waveform
- —–Pa: using a slow rate and nonrestricive high-pass filter (30-100Hz)
- –only ipsi recording because contra takes longer for the pathway and generators to mature so it will be ugly
AMLR and attention and state of arousal in children
- no attention to the stimuli means Pa amplitude decreases
* sleep means reduced amplitude (40% reduction) but pa latency is stable