Week 8 - Adherence Flashcards
What is compliance and what are some problems with it?
The extent to which the patient complies with medical advice
- Problems: patient does what they are told, doctor knows best, powerful doctor/passive patient
What is adherence?
The extent to which patient behaviour coincides with medical advice
- Attempt to be more patient-centred
- Need for agreement
- Patient’s right to choose
What is concordance?
- Negotiation between patient and doctor over treatment regimes
- Patients beliefs and priorities are respected
- Patient is active and can make decisions in partnership with the doctor
- Refers to the nature of the interaction between clinician and patient
Why is concordance better than adherence?
- Patient is involved in, and has shared ownership of, decisions about treatment
- Patients’ beliefs, expectations, lifestyle and priorities can be taken into account
- Barriers to adherence can be addressed
- Promotes patient trust and satisfaction with care
What are some non-adherence problems?
- Non-adherence to medical advice is the norm
- Chronic illness:
- – 50% are non-adherent
- – 10-25% of all hospital admissions are due to non-adherence
- Non-adherence to type of treatment regimen:
- – Medication: 20.6%
- – Exercise: 28%
- – Health behaviour: 31.3%
- – Diet: 41.7%
- Common even in more severe diseases and transplant patients
- – 22% of adult renal transplant patients are non-adherent to immunosuppressant medications
- – 91% of non-adherent patients experience organ rejection or death
- Highest rates of adherence
- – HIV, arthritis, GI disorders, cancer
- Highest rates of non-adherence:
- – Pulmonary disease, diabetes, sleep disorders
- Has an impact on patient’s health
- Financial implications
What are some problems with measuring adherence?
- What ‘counts’ as adherence
- – Not taking enough
- – Taking too much
- – Not taking at prescribed intervals
- – Taking some, but not all medication
- – Taking medication that is not prescribed
- Treatment not usually a ‘one-off’event
- – Usually continues over a period of time
- – When do we assess adherence?
- Lack of consistency in measures
- Hard to compare studies for different conditions with different medication or treatments
How can you directly measure adherence?
- Urine/blood test
— Advantages: provides most direct measure of consumption/adherence
— Disadvantages:
• Expensive
• Limited to use in clinical practice
• Invasive
• May be affected by metabolism
• Non-adherence may still be masked
• E.g. may only take medication properly just prior to tests
• Results aren’t available at time of test, so can’t discuss results with patient straight away - Observation
— E.g. watch them consume medication
— Similar problems to blood/urine tests
How can you indirectly measure adherence?
- Pill counts
— Subject to inaccuracy
• E.g. lost pills - Mechanical or electronic measures of dose
— E.g. record time at which container is opened
— Advantages: objectively measures whether a dose has been dispensed, more accurate than other indirect measures
— Disadvantages: doesn’t measure whether medication has actually been taken - Pharmacy
— See whether medication has been collected - Patient self-report
— Advantages: easy to obtain, inexpensive
— Disadvantages: prone to inaccuracies, bias, over-reporting adherence - Second-hand report:
— From doctors, carers, etc.
— Similar advantages and disadvantages to patient reports
— Depends on familiarity with patient
What is unintentional adherence?
- Arises from capacity and resource limitations that prevent patients from following treatment recommendations
- May be associated with individual constraints and/or associated with aspects of their environment
- – E.g. memory (individual)
- – E.g. problems with accessing prescriptions (environment)
What are some reasons for intentional adherence?
Arises from the beliefs, attitudes and expectations that influence patients’ motivation to begin and persist with the treatment regime
How can you address problems with adherence?
- Addressing practical barriers
- Addressing perceptual factors influencing motivation
What are some problems with interventions to improve adherence?
- Many lack theoretical input
- – Difficult to tell why some interventions work and others do not
- Few are truly ‘patient-centred’
- – Lack of individualising approach to match patients’ needs preferences
What are some factors that influence adherence?
- Illness
- Treatment
- Patient
- Psychosocial
- Healthcare
How can illness influence adherence?
- Symptoms
- – Adherence is usually better when patients experience symptoms
- Severity
- – Patients in poorer health are more likely to be adherent to less serious diseases than patients in better health
- – With more serious diseases, patients in poorer health are significantly less likely to be adherent
How can treatment influence adherence?
- Preparation
- – Treatment setting
- – Waiting time
- – Timing of referral
- – Convenience
- – Poor reputation
- Immediate character
- – Complexity of regimen
- – Duration of regimen
- – Degree of behaviour change
- – Convenience
- – Expense
- – Inadequate labels
- – Container design
- Administration
- – Supervision by healthcare professionals
- – Continuity of care
- Consequences
- – Physical side effects
- – Social side effects
- – Stigma