Week 8 - Adherence Flashcards

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1
Q

What is compliance and what are some problems with it?

A

The extent to which the patient complies with medical advice

- Problems: patient does what they are told, doctor knows best, powerful doctor/passive patient

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2
Q

What is adherence?

A

The extent to which patient behaviour coincides with medical advice

  • Attempt to be more patient-centred
  • Need for agreement
  • Patient’s right to choose
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3
Q

What is concordance?

A
  • Negotiation between patient and doctor over treatment regimes
  • Patients beliefs and priorities are respected
  • Patient is active and can make decisions in partnership with the doctor
  • Refers to the nature of the interaction between clinician and patient
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4
Q

Why is concordance better than adherence?

A
  • Patient is involved in, and has shared ownership of, decisions about treatment
  • Patients’ beliefs, expectations, lifestyle and priorities can be taken into account
  • Barriers to adherence can be addressed
  • Promotes patient trust and satisfaction with care
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5
Q

What are some non-adherence problems?

A
  • Non-adherence to medical advice is the norm
  • Chronic illness:
  • – 50% are non-adherent
  • – 10-25% of all hospital admissions are due to non-adherence
  • Non-adherence to type of treatment regimen:
  • – Medication: 20.6%
  • – Exercise: 28%
  • – Health behaviour: 31.3%
  • – Diet: 41.7%
  • Common even in more severe diseases and transplant patients
  • – 22% of adult renal transplant patients are non-adherent to immunosuppressant medications
  • – 91% of non-adherent patients experience organ rejection or death
  • Highest rates of adherence
  • – HIV, arthritis, GI disorders, cancer
  • Highest rates of non-adherence:
  • – Pulmonary disease, diabetes, sleep disorders
  • Has an impact on patient’s health
  • Financial implications
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6
Q

What are some problems with measuring adherence?

A
  • What ‘counts’ as adherence
  • – Not taking enough
  • – Taking too much
  • – Not taking at prescribed intervals
  • – Taking some, but not all medication
  • – Taking medication that is not prescribed
  • Treatment not usually a ‘one-off’event
  • – Usually continues over a period of time
  • – When do we assess adherence?
  • Lack of consistency in measures
  • Hard to compare studies for different conditions with different medication or treatments
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7
Q

How can you directly measure adherence?

A
  • Urine/blood test
    — Advantages: provides most direct measure of consumption/adherence
    — Disadvantages:
    • Expensive
    • Limited to use in clinical practice
    • Invasive
    • May be affected by metabolism
    • Non-adherence may still be masked
    • E.g. may only take medication properly just prior to tests
    • Results aren’t available at time of test, so can’t discuss results with patient straight away
  • Observation
    — E.g. watch them consume medication
    — Similar problems to blood/urine tests
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8
Q

How can you indirectly measure adherence?

A
  • Pill counts
    — Subject to inaccuracy
    • E.g. lost pills
  • Mechanical or electronic measures of dose
    — E.g. record time at which container is opened
    — Advantages: objectively measures whether a dose has been dispensed, more accurate than other indirect measures
    — Disadvantages: doesn’t measure whether medication has actually been taken
  • Pharmacy
    — See whether medication has been collected
  • Patient self-report
    — Advantages: easy to obtain, inexpensive
    — Disadvantages: prone to inaccuracies, bias, over-reporting adherence
  • Second-hand report:
    — From doctors, carers, etc.
    — Similar advantages and disadvantages to patient reports
    — Depends on familiarity with patient
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9
Q

What is unintentional adherence?

A
  • Arises from capacity and resource limitations that prevent patients from following treatment recommendations
  • May be associated with individual constraints and/or associated with aspects of their environment
  • – E.g. memory (individual)
  • – E.g. problems with accessing prescriptions (environment)
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10
Q

What are some reasons for intentional adherence?

A

Arises from the beliefs, attitudes and expectations that influence patients’ motivation to begin and persist with the treatment regime

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11
Q

How can you address problems with adherence?

A
  • Addressing practical barriers

- Addressing perceptual factors influencing motivation

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12
Q

What are some problems with interventions to improve adherence?

A
  • Many lack theoretical input
  • – Difficult to tell why some interventions work and others do not
  • Few are truly ‘patient-centred’
  • – Lack of individualising approach to match patients’ needs preferences
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13
Q

What are some factors that influence adherence?

A
  • Illness
  • Treatment
  • Patient
  • Psychosocial
  • Healthcare
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14
Q

How can illness influence adherence?

A
  • Symptoms
  • – Adherence is usually better when patients experience symptoms
  • Severity
  • – Patients in poorer health are more likely to be adherent to less serious diseases than patients in better health
  • – With more serious diseases, patients in poorer health are significantly less likely to be adherent
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15
Q

How can treatment influence adherence?

A
  • Preparation
  • – Treatment setting
  • – Waiting time
  • – Timing of referral
  • – Convenience
  • – Poor reputation
  • Immediate character
  • – Complexity of regimen
  • – Duration of regimen
  • – Degree of behaviour change
  • – Convenience
  • – Expense
  • – Inadequate labels
  • – Container design
  • Administration
  • – Supervision by healthcare professionals
  • – Continuity of care
  • Consequences
  • – Physical side effects
  • – Social side effects
  • – Stigma
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16
Q

How can the patient influence adherence?

A
  • Patient understanding of:
    — Information and content of the consultation
    — The illness, the body, treatment regimes
  • Recall
    — After GP consultation, patients may not recall:
    • Name of drug (37%)
    • Frequency of dose (23%)
    • Duration of treatment (25%)
    — Influenced by:
    • Anxiety
    • Knowledge
    • Importance
    • Primary/recency effect
    • Number of statements
  • From patients’ understanding to patients’ belief
  • Health belief model
    — Used to explain compliance with medical recommendations
    — The more a prescribed medication accords with a patient’s belief system, the more likely they are to adhere
    — Extent of adherence depends on:
    • Perceived disease severity
    • Perceived susceptibility to disease
    • Benefits of treatment recommended
    • Barriers of following treatment
  • Beliefs about illness
    — Severity
    — Symptoms
    — Understanding of illness as chronic vs episodic
  • Beliefs about medication
    — Necessity
    — Harmful effects
    • E.g. side effects, addiction
    — Stigma
    — Concerns about conflict with activities
    • E.g. alcohol, exercise
    — Tolerance
    — Masking symptoms
    — “Chemical”
    • Don’t want to take too many medications
  • Patients may reject/actively modify regimen or find alternative resources based on their beliefs and priorities
17
Q

How can psychosocial factors influence adherence?

A
  • Cognitive deficits or psychological problems can impact on compliance
  • Social support
  • – More socially isolated patients are less likely to adhere
  • – Social support is associated with higher adherence
  • – Family support: cohesive families associated with higher adherence than unstable families
  • Social context
  • – Homelessness = non-completion of therapy
18
Q

How can healthcare influence adherence?

A
  • Organisational setting
    — Primary vs secondary care
    — Initial vs follow up consultation
    — Links between inpatient and outpatient services
    — Regular follow up
    — Appeal and accessibility of venue
    — Waiting times
  • Prescriber
    — Their beliefs and attitudes towards treatments
  • Doctor-patient interaction
    — Perceived manner
    • Warm, caring, friendly, interested = associated with better adherence
    — Positive behaviours
    • Eye contact, smile, etc: associated with better adherence
    — Communication
    • Perceived poor communication is associated with higher non-adherence
    — Perceived competence
    • Interpersonal and technical competence associated with better adherence