Week 8 Flashcards

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1
Q

codon

A

set of 3 bases

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2
Q

how to read genetic code

A

left, top, right

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3
Q

what codon does translation start on

A

AUG on mRNA

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4
Q

what are the 3 stop codons

A

UAG, UAA, UGA
- dont code for amino acids

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5
Q

transcription

A

cells controll frequency of transcription

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6
Q

mrna processing

A

diff mrna may be reproduced from a single gene

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7
Q

translation

A

cells control rate of translation

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8
Q

modification

A

cells can regulate a protein’s activity by modifying

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9
Q

degradation

A

cells can regulate a protein’s activity by degrading it

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10
Q

protein synthesis

A

creates protein molecules
- “centrazl dogma”

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11
Q

rna polymerase

A

synthesizes rna froma template of dna thru transcription
- needed for transcription

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12
Q

adjacent thymine

A

cuases residues (dimmers) on same strand of dna/distortion of one dna strand
- causes dna replication to halt
- can be from overexposure to UV rays

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13
Q

epigenetic

A

not a mutation in dna

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14
Q

gene silencing

A

block transcription/translation = no protein

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15
Q

what are chem alterations in dna

A

methylation; histone moldification can affect the dna packing/impact way we express our genes

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16
Q

dna methylation creates long lasting …. and is result of ….

A

changes in gene promoters; drug abjuse

17
Q

dna is … to mrna and then … to proteins

A

transcribed; translated

18
Q

antisense olignucleotides

A

complementary bind to transcribed mrna and will halt the translation process

19
Q

.. carries all the amino acid seqeunces needed to create proteim

A

exons

20
Q

dna replication happens where

A

Ori site (origin site)

21
Q

in transcription, mrna needs to be

A

synthesized

22
Q

promoter

A

beginning of gene

23
Q

terminator

A

end of gene

24
Q

we need intronms to avoid the risk of

A

mutations

25
Q

spliceosome

A

removes introns
- mrna shortened so translations can happen = protein

26
Q

transcription happens

A

in nucleus
- creates mrna

27
Q

translation happens

A

in cytoplasm
- creates protein

28
Q

we need ribosomal structurew

A

large/snmall subunit to create proteinms
- large = catalystic
- small = binding site for amino acids, mrna, trna

29
Q

trna is … pairing

A

base
- temp association need for trna to bind to region `

30
Q

.. bonds are created b/w amino acids

A

peptide bonds
- ribosomes allow them to form

31
Q

3 sites

A

exit site; peptide site; amino assign site

32
Q

peptides

A

short chains of amino acids
- building block of proteins

33
Q

a .. will cuase a change in mrna

A

mutation

34
Q

bacteria have a lack of …

A

introns
- also have enzymes that make them resistant
- susceptible to antibiotic

35
Q

dna polymerasze needed for

A

dna replication to create dna/rna

36
Q

rna polymerase needed for

A

transcription to create mrna, trna, rrna

37
Q

antibiotics

A

inhibit rna polymerase = no protein

38
Q

release factor

A

allows for the termination of translationm by recognizing stop codon in mrna sequence