Week 7 - Thursday

Question 1

What do activators recognize

Answer 1

enhancers

Question 1

Are activators and repressors proteins or DNA

Answer 1

proteins

Question 2

What do repressors recgonize

Answer 2

Silencers

Question 3

What 3 things control transcriptional regulation?

Answer 3

1. Promoter strength
2. Regulatory elements
3. RNA silencing

Question 4

What is RNA silencing

Answer 4

Post transcriptional regulation
-targeted degradation of mRNAs w/ miRNA

Question 5

what does miRNA do?

Answer 5

Silences genes by cutting up mRNA
-only degrades seq. that are complementary

Question 6

Transcriptomics

Answer 6

Study of RNA expression levels across the genome

Question 7

Combinatorial control

Answer 7

The integration of many inputs into an output

Question 8

Direct response

Answer 8

Cell phenotype changes as a direct result of environmental trigger

Question 9

Gene mediated response

Answer 9

Cell phenotype changes after environmental trigger turns gene on or off
-molecule usually used

Question 10

What kind of response causes the coat coloration plasticity in Siamese cats

Answer 10

Direct response

Question 11

Why do we not use GWAS in determining seasonal coat color? What do we use instead?

Answer 11

There is no mutation change in the animal instead there is a change in expression levels
-RNA seq