Week 7 Revision Flashcards

1
Q

What is unipolar depression?

A

having symptoms of depression only

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2
Q

What is bipolar depression?

A

Having periods of depression with periods of mania. Mania is characterised by sudden outburst of activity, rapid speech & thinking, expanded optimistic ideas

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3
Q

List two common symptoms of depression?

A
  • Low mood

- Loss of appetite

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4
Q

What can be a severe symptoms of depression?

A

They may expereince withdrawl from reality with psychotic symptoms in bipolar depression

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5
Q

What gender is more common with sucide?

A

More women attempt suicide, more males succeed.

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6
Q

When does post partum depression occur? How long can it last for?

A

Peaks between 3 to 6 weeks after the baby is delivered. Post partum depression can occur up to 6 months post birth & can last for most of the first year

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7
Q

What is seasonal affective disorder?

A

Depression that occurs in the winter months due to the shorter day and less light. During the dark noradrenaline levels rise

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8
Q

What is serotonin?

A

A neurotransmitter - levels of this can reduce in depression. Low levels can be associated with violent behaviour against other. This also is associated with lower levels of noradrenaline in the brain

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9
Q

What is noradrenaline? How does it relate to depression?

A

A seconday neurotransmitter - there is a lack of noradrenaline receptors in depression

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10
Q

What hormones are affected by patients with depression?

A

There will be a lower level of growth hormones and thyroxine

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11
Q

What % of dementia is caused by a reduced blood supply to the brain?

A

25%

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12
Q

What are the two neurotransmitters involved in depression?

A

Serotonin and noradrenaline

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13
Q

What causes someone memory to become worse when they age?

A

There is a change in the synapses between nurones. The nurones then begin to slowly die, adn the synpatic connection is lost, resulting in memories going.

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14
Q

What is anterograde?

A

Memories go first

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15
Q

What is retrograde?

A

Memories lost at a later date

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16
Q

What 2 things happen to the brain when someone has dementia?

A

1) extreme shrinkage of cerebral cortex

2) severely enlarged ventricles

17
Q

List 2 features of memory loss

A

1) Problems remembering recent events

2) Organisation problems

18
Q

What is alzheimers disease?

A

Plaques between neurons & tangles in neuron cell bodies.

19
Q

What is vascular dementia (post-stroke dementia)?

A

Sudden loss of function of large area of brain due to clot/bleed of major artery.

20
Q

What is vascular dementia (sub-cortical demenetia)?

A

Restriction to blood flow in small arteries in white matter.

21
Q

What are lewy bodies?

A

Small protein deposits in nerves seen in Parkinson’s Disease

22
Q

What are 2 rare types of dementia?

A

1) Pick’s Disease

2) Posterior Cortical Atrophy

23
Q

What age does early alzheimers dementia typically occur?

A

between 60 and 70 years of age

24
Q

What 3 genes are associated with alzheimers disease?

A

Presenilin-1 (PS1) (most common)
Amyloid βA4 protein (APP)
Presenilin-2 (PS2) (very rare)

25
Q

What are two anti-dementia medications? How are they given?

A

Donepezil
Memantine

Diagnosis and treatment by a specialist

26
Q

What are the two pathological changes in the brain due to Alzheimer’s disease?

A

extracellular plaques

intracellular neurofibrillary tangles

27
Q

What are three common signs of dementia?

A

Confusion
Self-neglect
Amnesia

28
Q

What is agglutination?

A

the clumping together of red blood cells due to binding of antigens and antibodies