Brainscape's Knowledge GenomeTM


Top Flashcards (Certified)
All Flashcards

TERM 3 N2161 KNLG 2 > WEEK 7 & 8 ANTIDIABETIC DRUGS > Flashcards

WEEK 7 & 8 ANTIDIABETIC DRUGS Flashcards

1
Q

Name one example of an alpha-glucosidase inhibitor

A

acarbose (Glucobay)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

What is another term for alpha-glucosidase inhibitors?

A

Starch blockers

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

What is the action of alpha-glucosidase inhibitors?

A

Inhibits the enzyme alpha-glucosidase to prevent the breakdown of starch into glucose

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

What is the therapeutic effect of alpha-glucosidase inhibitors?

A

Lowers postprandial blood sugar

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

Name 2 side effects of alpha-glucosidase inhibitors

A
  1. Flatulence
  2. GI upset
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

Name one example of a biguanide

A

metformin (Glumetza)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

Name 3 actions of biguanides

A
  1. Inhibits hepatic glucose production
  2. Inhibits intestinal glucose absorption
  3. Increases insulin sensitivity
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

What are 2 side effects of biguanides?

A
  1. GI upset
  2. Metallic taste
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

What are 2 reasons the nurse should hold a biguanide drug?

A
  1. Patient receiving iodinated contrast
  2. Patient is not eating/drinking
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

Name 1 example of an incretin mimetic

A

exenatide (Byetta)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

What are 4 actions of incretin mimetics?

A

Mimics action of incretin:
1. Increases insulin secretion
2. Decreases glucagon
3. Decreases gastric emptying
4. Increases satiety

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

What are 3 side effects of incretin mimetics?

A
  1. GI upset and weight loss
  2. Headache
  3. Hypoglycemia
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

What are 2 contraindications for incretin mimetics?

A
  1. Pancreatitis
  2. Severe GI disease
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

What are 2 guidelines for administration of incretin mimetics?

A
  1. Immediate release forms cannot be taken after meals
  2. Keep refridgerated
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

Name 2 examples of meglitinides

A
  1. repaglinide (Gluconorm)
  2. nateglinide (Starlix)
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

What is another term for meglitinides?

A

Nonsulphonylureas

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
17
Q

What is the action of meglitinides?

A

Stimulates beta cells of pancreas to release insulin

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
18
Q

What is one side effect of meglitinides?

A

Hypoglycemia

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
19
Q

What is one contraindication for meglitinides?

A

Patient is not eating/drinking

20
Q

What are 2 guidelines for administering meglitinides?

A
  1. Take up to 30 minutes before eating
  2. Doses may be added/skipped as needed with meals
21
Q

Name 2 examples of sulphonylureas

A
  1. glyburide (Diabeta)
  2. gliclazide (Diamicron)
22
Q

What is another term for sulphonylureas?

A

Insulin secretagogues

23
Q

Name 2 actions of sulphonylureas

A
  1. Stimulates release of insulin
  2. Increases insulin sensitivity
24
Q

Name 2 side effects of sulphonylureas

A
  1. Weight gain
  2. Hypoglycemia
25
Name a contraindication for sulphonylureas
Allergy to sulpha drugs
26
What is one guideline to remember when administering sulphonylureas?
High alert medication
27
Name 1 example of a thiazolidinedione
pioglitazone (Actos)
28
What are 2 other terms for thiazolidinediones?
1. Glitazones 2. Insulin sensitizers
29
What is the action of thiazolidinediones?
Acts as an agonist for insulin at receptor sites
30
Name 3 side effects of thiazolidinediones
1. Edema 2. Weight gain 3. CHF
31
Which insulin is rapid acting?
Insulin lispro
32
What is the brand name for insulin lispro?
Humalog
33
When is the peak of action for insulin lispro?
60-90 min
34
Which insulin is short acting?
Insulin regular
35
What is the brand name for insulin regular?
Humulin R
36
What are 2 routes for insulin regular?
SC or IV
37
What is the peak of action for insulin regular?
2-4 hr
38
Which insulin is intermediate acting?
NPH insulin
39
What is the brand name for NPH insulin?
Humulin N
40
What is the peak of action for NPH insulin?
6-8 hr
41
What are 2 examples of long acting insulin?
1. Insulin glargine 2. Insulin detemir
42
What are 3 brand names for insulin glargine?
Lantus Basaglar Toujeo
43
What is the brand name for insulin detemir?
Levemir
44
When is the peak of action for long acting insulins?
None
45
For premixed insulins like Humulin 30/70, what do the numbers indicate?
First number is regular insulin, second number is NPH insulin

TERM 3 N2161 KNLG 2 (13 decks)

Brainscape helps you reach your goals faster, through stronger study habits.
© 2025 Bold Learning Solutions. Terms and Conditions