Week 6 - Toxicology Intro - CBRNE Flashcards

1
Q

Toxicology 101

What dose ABCDEF stand for?

What does RRSIDEAD

A

A =Airway
B = Breathing
C = Circulation
D = Decontamination
E = Elimination
F = Find the Antidote

R = Resuscitation
R = Risk Assessment
S = Supportive Care
I = Investigations
D = Decontamination
E = Enhance Elimination
A = Antidotes
D = Disposition

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2
Q

What does CBRNE vibes?

A

Chemical
Biological
Radiological
Nuclear
Explosive

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3
Q

WMD - Weapon of Mass Destruction

What’s the definition?

What are considered WMDs

A

A nuclear, radiological, chemical, biological, or any other weapon that can kill and bring significant harm to numerous humans or cause great damage to human-made sturctures, natural structures, or the biosphere

Toxic or poisonous chemicals

Disease organism

Radiation or radioactive material

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4
Q

What is the definition of terrorism?

A

The unlawful use of force and violence against persons or property to intimidate or coerce a government (the civilian population or any segment therof) to further political or social objectives/goals

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5
Q

What are the Standards to know in regards to CBRNE?

What are treatments to nerve agents?

What are examples of nerve agents?

A

Opioid Toxicity & Withdrawal
PCP Auxiliary

Cyanide Exposure (IV Autonomous)

Hydrofluoric Acid Exposure

Adult & Pediatric Nerve Agent Exposure

Symptomatic Riot Agent Exposure

Atropine
2-PAM - Pralidoxime Chlroride

SARIN
VX
Novichok
Organophosphate Insecticides

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6
Q

Cholinergic Crisis

What does SLUDGE M stand for?

A

S = Salivation

L = Lacrimation

U = Urination

D = Defecation

G = Gastrointestinal distress

E = Emesis

M = Miosis (pupil constriction)

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7
Q

Show me what the sympathetic and parasympathetic nervous sytem control

A
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8
Q

Antocholingeric Overdose

What’s the Toxidrome acronym?

A

MAD
HOT
BLIND
DRY
RED

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9
Q

Show me a list of drugs with moderate - strong anticholinergics effects.

A
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10
Q

Give me a quick overview of cholinergic vs anticholinergic syndrome presentation in a pt.

A
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11
Q

Types of gases

What is Silo Gas?

A

nitrogen dioxide, NO2 - this gas can be exposed to farmers

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12
Q

Types of gases

Sewer gas?

A

Mostly hydrogen sulfide gas (H2S) which is deadly at low concentrations.

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13
Q

What types of calls could involve CBRNE?

A

Industrial

Farm

Pediatric

Youth Risky Behaviors (Pill Parties)

Polypharmacy

Alcohol with anything and everything

Accidental exposure or ingestion

Intentional exposure of ingestion

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14
Q

Pills/medications

What are the top 6 questions/observations?

A

Date Prescribed (original bottle ?)

Dose

Frequency

Remaining amount

Co-Ingestion?

Alcohol?

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15
Q

Overdose Treatments

What’s the treatment for cocaine?

Heroine?

Show me the symptoms of cocaine overdose

A

Benzos - midazolam

narcan, support the breathing

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16
Q

Common overdoses

Show me waht medications have the most often/occuring overdoses

A
17
Q

Tylenol overdose

?

What’s the treatment?

A

GREATER than 4000mg in 24h

N-acetylcysteine (NAC)

Mucomyst

Given within 8 hours of ingestion

18
Q

4 Stages of Acetaminophen Toxicity

Define Stage 1?

Define Stage 2?

A

Characterized by
nausea vomiting
nonspecific right upper abdominal pain

These symptoms begin within a few minutes to
hours after Tylenol consumption.

This stage appears on days 2-3 with the initial symptoms decreasing and liver symptoms increasing (upper abdominal pain - increased liver enzymes)

19
Q

4 Stages of Acetaminophen Toxicity

Define Stage 3? What are the symptoms?

Define Stage 4?

A

This stage occurs on days 3-4 where peak liver injury occurs further affecting other body organs (due to the lack of toxins being neutralized/excreted)

Brain dysfunction (encephalopathy)

Yellow color to eyes and skin (jaundice)

Inability to clot blood (coagulopathy)

Too much acid in the blood (metabolic acidosis)

Low blood glucose (hypoglycemia)

This is the stage in which people begin to recover IF they survive past stage 3

20
Q

Activated Charcoal

What is it/and its use?

A

The administration can only occur when the position of the nasogastric tube is confirmed via chest x-ray.

It helps prevent the poison from being absorbed from the stomach into the body