Week 6- Pharmacology Flashcards
What is pharmodynamics?
the study of the biochemical and physiological effects of drugs and their mechanisms of action
- what the DRUG does to the body.
What is pharmacokinetics??
the study of how the body interacts with administered substances for the entire duration of exposure
- what the BODY does to the drug.
What is pharmacotherapeutics?
the use of drugs for the prevention, treatment, diagnosis, and modification of normal functions.
Eg pregnancy prevention
What is toxicology?
the study of the adverse effects of chemicals or physical agents on living organisms.
DRUG EFFECT definition: therapeutic?
beneficial treatment
DRUG EFFECT definition: side effects?
unwanted reactions (generally mild)
DRUG EFFECT definition: toxic effects?
dangerous side effects
DRUG EFFECT definition: hypersensitivity?
allergic reactions
DRUG EFFECT definition: idiosyncratic?
unusual reaction by an individual to a normally harmless substance
DRUG EFFECT definition: latrogenic?
negative effect caused by error or OD
DRUG EFFECT definition: tetratogenic?
harmful effects on a fetus
INTERACTIONS: What is synergism?
substance that produces an effect that is MORE than expected!! (2+2= 10)
- increased effect
- could be good or bad
INTERACTIONS: What is antagonism?
opposing action, TWO meds
- only half works, blocking receptors
INTERACTIONS: What is potentiation?
to increase the strength or effect (one med does NOTHING, the other med is supersized!!)
INTERACTIONS: What is additive?
combining 2 meds and they work together happily!!!
( Tylenol and Advil they work together so they are HAPPY!!)
What is the goal of drug absorption?
from its site of administration into the body to specific target organs and tissues
ultimate goal is reaching a therapeutic concentration into the bloodstream!!
What are the 2 mechanisms of medication absorption?
active transport
passive diffusion
Define: distribution of medication?
process by which a medication moves throughout the body
What is the PRIMARY distribution vehicle of drugs?
BLOOD!!
What is biotransformation?
manner in which the body metabolizes medication > first pass effect
What is excretion?
when the body eliminates the remnants of the drug
What are three mechanisms of excretion in the kidneys?
glomerular filtration
tubular secretion
partial reabsorption
What is the chronotropoic effect on the cardiovascular system?
changes HR
What is the inotropic effect on the cardiovascular system?
changes the CONTRACTILITY of the heart