Week 6: Memory Systems Flashcards

1
Q

What is learning?

A

the process

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2
Q

What is memory?

A

the outcome

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3
Q

What are the 3 memory stages?

A
Encoding = acquisition and consolidation
Storage = permanent representation is stored
Retrieval = retrieved back into conscious awareness
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4
Q

What are the 4 types of memory?

A

Sensory
STM & Working
LT Non-Declarative
LT Declarative

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5
Q

What is LTM?

A

LTM has no limit and may last a lifetime
Declarative is the conscious type e.g. who is the PM
Non-declarative is the unconscious type (just do it)

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6
Q

How do you increase STM capacity?

A

Try to avoid decay through chunking

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7
Q

What is habituation?

A

decrease in response with repeated exposure

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8
Q

What is sensitisation?

A

increase in response with repeated exposure

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9
Q

How is the MTL important for memory?

A

Hippocampus, parahippocampal, entorhinal and perirhinal cortices make up the MTL
Damage can result in amnesia

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10
Q

What are the subcortical structures that are important for memory?

A

Fornix
Mammillary bodies
Anterior thalamic nuclei
Amygdala - which encodes content of experiences (fear learning)

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11
Q

What are the cortical structures important for memory?

A

Prefrontal cortex - storage and retrieval, episodic memories

Inferotemporal cortex - storage of visual observations

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12
Q

Why is the cerebellum important for memory?

A

Important for conditioning (e.g. Pavlov)

Activities such as riding a bike

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13
Q

Why is the striatum important for memory?

A

Has the basal ganglia, important for implicit (non-declarative) memories and habit formation

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14
Q

What are the 2 domains of sensory memory?

A

Echoic - auditory - 9-10sec

Iconic - visual - 300-500ms

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15
Q

What is the modal model of STM?

A

By Atkinson & Shiffrin
Sensory input –> sesnory register –> short term storage with the assistance of attention –> Long term storage with the assistance of rehearsal

Info can be lost at the short-term storage stage through decay or interference

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16
Q

What are the 3 components of the Baddeley & Hitch 1974 Working Memory Model

A

Central Executive

Phonological Loop: acoustic code, acoustic store and articulatory loop

Visuospatial Sketch Pad (VSSP): visual or visuospatial code

17
Q

What are the regions responsible for phonological working memory?

A

Supramarginal gyrus - phonological WM

Premotor region - rehearsal in phonological loop

18
Q

What are the regions responsible for VSSP?

A

Bilateral parietal occipital region

19
Q

What is the story of HM?

A

Had a bilateral resection of MTL for epilepsy which included the hippocampus and amygdala
Led to severe anterograde amnesia and retrograde amnesia of up to 2 yrs prior
However he had a spared STM and non-declarative memroy

20
Q

True or False

Amnesiacs can show normal implicit learning and non-declarative knowledge

21
Q

What is Global Cerebral Ischemia?

A

Interruptions of blood supply to the brain

Can lead RB to dense anterograde and retrograde amnesia of approx. 1-2yrs

22
Q

What is Transient Global Amnesia?

A

Disruption of blood flow to MTL and diencephalon
Is a short term syndrome of 4-6hrs
Lead to sudden anterograde and variable retrograde amnesia 24-48hrs

23
Q

What is Korsakoff’s Syndrome?

A

Is caused by chronic consumption of alcohol.
Dorsomedial nucleus of thalamus and mammillary bodies are implicated in the syndrome
It is the result of a thiamine deficiency
Leads to severe anterograde & retrograde amnesia: ret is more effected and disrupted and greater loss of declarative

24
Q

Explain Alzheimers Disease

A

The first symptom is minor loss of memories but becomes more extreme
Pathological changes include Amyloid plaques and neurofibrally tangles; degeneration of basal forebrain and reduced acetylcholine

25
What is Posttraumatic Amnesisa?
Memory loss following closed heady injury, with a blow to the head can result in a concussion and/or coma The result is both anterograde and retrograde amnesia
26
What region coordinates the consolidation process?
Medial Temporal Lobe
27
What have ECT studies shown about consolidation?
Consolidation may take years to occur
28
What role does the hippocampus play in consolidation?
Hippocampus holds until it is stored elsewhere. | The current view is that the hippocampus stores memories every time it is recalled
29
What did the Mumby Box show?
Shows that the Medial Temporal Cortex removal results in severe deficits in object recognition However the removal of hippocampus and amygdala does not
30
What does the Morris Water Maze Reflect?
reflects the importance of the hippocampus for relational/contextual information
31
What are the 2 main neurons of the MTL and memory?
Hippocampal Place Cells | Entorhinal Grid Cells
32
What is a hippocampal place cell?
Fires when rat is at specific location; there is a specific cell for each place The rat knows where it has been before so spikes electrical signal in neurons. Forming the map for the rest of the brain telling you where you are in the environment
33
What are entorhinal grid cells?
Represent evenly spaced place fields sending signals to the hippocampus. They are similar to place cells, but fires in array of different location and help you remember the path taken to help you return where you need to be.
34
What are the other cells of the hippocampus?
Time cells Engram Cells Social space Concept cells (Jennifer Aniston Neurons)