Week 5 - Nervous System Flashcards
outside the central nervous system
-clusters of cell bodies are called ganglion
-groups of axons are called nerves
inside the central nervous system
-groups of cell bodies are called grey matter
-a collection of axons is called a tract
-a group of trats is called white matter
somatic nervous system
efferent neurons under voluntary control
autonomic nervous system
efferent neurons under involuntary control
sympathetic
emergency system: increase heart rate, bronchodilation, decrease peristalsis, increased sweat gland secretion, inhibit voiding
parasympathetic
control under normal conditions: decrease heart rate, bronchoconstriction, increase peristalsis, increase digestive juice secretion (including saliva), micturition reflex, defecation reflex
meninges
set of connective tissue membranes that surround the central nervous system (brain and spinal cord)
-from inside to out: PAD
-pia mater, arachnoid mater, dura mater
meninges functions
cover and protect the CNS, protect blood vessels and enclose venous sinuses, contain CSF found between the arachnoid mater and pia mater, form partitions within the skull
functions of cerebrospinal fluid
forms a liquid cushion that gives buoyancy to the CNS organs, prevents the brain from crushing under its own weight, protects the CNS from blows and other trauma, nourishes the brain and carries chemical signals throughout it
cerebrum
controls our ability to read, write, think, speak, remember, feel, and move; interpretation of sensory information; motor function
-four external lobes: frontal, parietal, temporal, occipital lobes
thalamus
receives and passes on sensory information; sorts out, edits, and relays impulses of similar function; associated with the interpretation of pain and pleasure
hypothalamus
controls the autonomic nervous system and production of hormones by acting on the pituitary gland
brain stem
controls automatic behaviours necessary for survival
-midbrain, pons, medulla oblongata
midbrain
reflex center for head and eye movements in response to sight and sounds
pons
all sensory and motor fibers pass through the pons; helps to regulate breathing
medulla oblongata
crossover of motor fibers
-cardiovascular center – regulates heart rate
-respiratory center – regulates rate and depth of breathing
-vasomotor center – regulates blood pressure
-also regulates swallowing, sneezing and vomiting
cerebellum
coordination; maintains posture; maintains equilibrium using sensory input from inner ear (balance)
functions of spinal cord
- carries information
-sensory impulses from periphery to brain
-motor impulses from brain to periphery - integrating reflexes
-reflex centers for faster response for a particular stimulus
-passes a nerve impulse from a sensory neuron to a motor neuron
reflex arc
fast, automatic, unplanned sequence of actions in response to a stimulus
components of a reflex arc
- receptor detects change in environment and initiates a nerve impulse
- sensory neuron passes the impulse to the spinal cord
- spinal cord integrates the message and passes it directly to a motor neuron
- a motor neuron transmit the nerve impulse to the effector
- the effector responds to the nerve impulse (the response = reflex)
resting membrane potential
present in all cells; the inside of the plasma membrane is negative relative to the outside of the plasma membrane
3 resting membrane potential key factors
- action of sodium-potassium pump: 3 Na+ pumped out for every 2K+ pumped in
- intracellular protein anions are trapped
- plasma membrane is more permeable to potassium than to sodium
leakage channels
random opening and closingl
ligand-gated channels
open with binding of a specific neurotransmitter
mechanically-gated channels
open or close in response to mechanical stimulation
voltage-gated channels
open and close in response to membrane potential
phases of action potential
- resting state (resting membrane potential)
- depolarization (Na+ gates open)
- repolarization (voltage-gated Na+ channels close and voltage-gated K+ channels open) and K+ rush out of the cell
- hyperpolarization (voltage-gated Na+ channels are reset, but voltage-gated K+ channels remain open for slightly longer) - as a result the membrane potential dips
events at the synaptic cleft
- the action potential reaches the axon bulb of the presynaptic neuron
- this activates voltage-gated Ca2+ channels to open, allowing Ca2+ to flood in
- Ca2+ causes synaptic vesicles that contain a specific neurotransmitter to move to the axon end and the vesicles fuse with the membrane, resulting in exocytosis of the neurotransmitter into the synaptic cleft
- neurotransmitters diffuse across the synaptic cleft and bind to ligand-gated channels on the postsynaptic neuron
- these ligand-gated channels open and Na+ rushes in, starting an action potential on the postsynaptic neuron