Week 7 - Integumentary System Flashcards
skin
one of the largest organs of the body
protection
-mechanical protection -> keratin in the outermost layer
-prevents dehydration -> lipid secretions from cells and glands
-UV radiation protection -> melanin in melanocytes and keratinocytes absorb UV radiation
-antimicrobrial effect
body temperature regulation
helps in regulating body temperature; sudoriferous glands produce sweat to reduce heat
sensation
contains various receptors which detect stimuli: mechanoreceptors, thermoreceptors, nociceptors
excretion
removes waste products (eg. salts, urea, ammonia, CO2) from the body; sweating removes a variety of chemical wastes, in small amounts
synthesis of vitamin D
UV radiation from sun stimulates the skin to convert an inactive form of vitamin D to an active form; vitamin D is needed to absorb calcium
epidermis
-keratinocytes (~90%): produce keratin, which protects and keeps the skin waterproof
-melanocytes (~8%): produce melanin, one of the major pigments responsible for skin colour, also protects the skin from UV rays
layers of the epidermis
stratum corneum, stratum lucidum, stratum granulosum, stratum spinosum, stratum basale
stratum corneum
flat, closely packed, dead keratinocytes (20-30 layers of cells), keratin instead of cytoplasm, glycolipids in extracellular space; the layer that is shed during abrasion
stratum lucidum
only in areas where the skin is thick (palms, soles, fingers); clear, flat, dead keratinocytes that contain eleidin which will eventually transform into keratin
stratum granulosum
three to five rows of flattened, dying keratinocytes, losing nuclei and organelles; contains granules of keratohyalin
stratum spinosum
eight to ten rows of live keratinocytes and melanocytes packed tightly together containing pre-keratin; surfaces of cells appear to look spiny
stratum basale
rapidly dividing keratinocytes and melanocytes to replenish the cells above it; single row of cuboidal or columnar cells
dermis
deep to the epidermis;
-papillary region: loose areolar connective tissue; contains blood vessels and sensory receptors
-reticular region: dense irregular connective tissue with bundles of collagen and elastic fibers; gives the skin its strength, flexibility, and elasticity
hypodermis
deep to the dermis; contains adipose tissue and blood vessels; not considered part of the skin