Week 5 Flashcards
What is acute coronary syndrome?
Any acute presentation of coronary artery disease e.g angina, MI
How can ACS occur?
Due to rupture of the atheromatus plaque, from lipid content of plaque, thickness of fibrous cap, change in pressure, twisting of arteries, mechanical injury
Man presents acutely with MI what is your treatment?
MONA T
Morphine (antiametic)
Oxygen
Nitrates (GTN)
Aspirin (300mg)
Ticagrelor
Man presents with ST elevation MI, its been less than 20 minutes, what is the treatment?
MONA plus T
Coronary angioplasty
If more than 4 hours give thrombolysis
Man presents with non-ST elevation MI, treatment?
Mona plus T
In the capillaries what is the main starling force that governs entry and exit of materials from capillary to lumen?
Outwards; capillary hydrostatic pressure (result of BP in capillary)
Inwards; capillary osmotic pressure (due to pressure of plasma proteins in the blood)
What are some of the causes of left sided heart failure?
Ischaemic heart disease
Dilated Cardiomyopathy
Valvular disease
Man presents with dysponea on exertion, orthopnoea, paroxysmal dyspnoea, pulmonary oedema. On examination, has tachycardia, crepitations and a third heart sound with galloping rhythm. What is the diagnosis?
Left sided heart failure
What is the treatment for left sided heart failure?
Sit them up Give oxygen IV Furosemide (diuretic) IV Diamorphine IV nitrates
LMNOP (loop diuretic, morphine, nitrates, oxygen, position),
Women present with oedema in ankles, a raised JVP, enlarged liver, ascites. She is known to have COPD
Right sided heart failure
What are the drugs in the ACE inhibitors
Captopril
Enalapril
Lisinopril
You suspect an MI, what blood tests would you order?
Troponin
CK
Define an ectopic beat
Beats of rhythms that originate in places other than the SA node
What is wolf parkinson white syndrome?
Where there is more than one conduction pathway of the heart with a different speed of depolarisation causing delta waves to be present ( on the qrs complex it has two different gradients)
What factors can increase phase 4 of the cardiac myocyte action potential? AKA increase heart rate
Hyperthermia Hypoxia Hypercapnia Cardiac dilation Hypokalaemia (prolonging repolariszation)
What is the arrhythmia torsades de pointes
A type of ventricular tachycardia in people with long QT intervals. Will look like quick irregular QRS complexes. This can progress to VF
What would you use a 24 hr holter ECG to investigate?
Paroxysmal arrhythmia
Patient is classed as bradycardic, what is his heart rate?
Less than 60
AV nodal re-entrant tachycardia, Av reciprocating tachycardia and ectopic atrial tachycardia. Are all causes of what arrythmia?
Regular supraventricular tachycardia
Describe the treatment for a supraventricular tachycardia
Increase vagal tone by the valsava maneouvre (closing nose and breathing against it), carotid massage
Slowing down AVN conduction by adenosine IV or verapamil IV
What is radiofrequency catheter ablation?
Selective cauterisation of cardiac tissue to prevent tachycardia- targeting an automatic focus of re-entry circuit