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Scientific Basis > Week 5 > Flashcards

Week 5 Flashcards

1
Q

What does NSAID mean?

A

Non-steroid anti-inflammatory drugs

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2
Q

What does Aspirin interact with?

A 
Anti-coagulant - warfarin/heparin
Glucocorticoids 
Alcohol
Ibuprofen 
ACE inhibitors, angiotensin receptor blockers
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3
Q

What are adverse effects for Celecoxib (Celebrex)?

A 
Dyspepsia - upper gut pain
Abdominal pain 
Renal toxicity
Sulfonamide allergy
Cardiovascular impact - stroke, MI, and other serious events
Use in pregnancy
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4
Q

What are the adverse effects of Glucocorticoids?

A 
Adrenal insufficiency 
Osteoporosis 
Infection 
Glucose intolerance 
Myopathy 
Electrolyte disturbance 
Growth retardation 
Glaucoma and Cataracts
Peptic ulcer disease
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5
Q

Treatment for Gout

A

NASAID- pain/ inflammation

Glucocorticoids-effective alternative if pt has renal disease

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6
Q

Types of cells in nervous system (2)

A

Neurons and glia

Neuron structure and function

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7
Q

Major division of nervous system

A

Central nervous system

Peripheral nervous system - somatic/ autonomic

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8
Q

What is the Neurons role?

A

Process information - sense environmental changes/communicate to other Neurons

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9
Q

What is the glia role?

A

Insulate, support and nourish Neurons

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10
Q

Parts of the Neuron?

A

Soma - cell body
Dendrites
Axon

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11
Q

The autonomic nervous system consists of? (2)

A

Sympathetic and Parasympathetic

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12
Q

(3) types of tissue

A

Glands
Smooth Muscle
Cardiac Muscle

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13
Q

Autonomic Nervous System - Sympathetic anatomy

A

Branch from thoracic and lumber spinal nerves

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14
Q

Autonomic Nervous System - Parasympathetic Anatomy

A

Cranial Nerves - 3, 7, 9, 10

Pelvic Nerves exiting from s2-s4

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15
Q

Function of the Sympathetic route

A

Mobilise body for short term emergencies
Fight or flight - fright or sex’
Increase heart rate
Glucose mobilisation

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16
Q

Function of the Parasympathetic

A

Works calmly for long term good
Rest and digest
Facilitates digestion, energy storage, growth, immune response.
Decreases heart rate, increase gut motility (digestion)

17
Q

What types of tissue does the sympathetic and parasympathetic nervous system innervate?

A

Cardiac Muscle
Smooth Muscle
Glands

18
Q

Neurotransmission - types of synapses (2)

A

Electrical (rare)

Chemical

19
Q

Sympathetic Neurotransmitters (3)

A

ACh - acetylcholine
E - (epinephrine) - adrenaline
NE - (norepinephrine) - noradrenaline

20
Q

Neurotransmission receptors (2) categories

A

Cholinergic receptors - respond to acetylcholine

Adrenergic receptors- respond to adrenaline and noradrenalin

21
Q

Receptor sub types (2)

A

Alpha

Beta

22
Q

Which neurotransmitter does the parasympathetic nervous system use?

A

Acetylcholine

23
Q

What does Cox mean?

A

Cyclo-oxygenase

24
Q

What is a Ganglionic?

A

Connection of 2 nerves

Scientific Basis (6 decks)

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