Week 3

Question 1

Types of tolerance (2)

Answer 1

Metabolic

Pharmacodynamic

Question 2

Definition of poisoning?

Answer 2

A pathological state caused by a toxic agent.
Toxic agent can be a medicine, plant, environmental pollutants, drugs of abuse.
Routes of entry can be Oral, inhalation, absorption via the skin, intravenous.
Accidental or Intentional.

Question 3

What is Polypharmacy?

Answer 3

Mixture of drugs

Multiple medications being taken

Question 4

What does activated charcoal do?

Answer 4

It binds to the poison and helps to remove without causing anymore damage within the body.

Question 5

What is gastric lavage?

Answer 5

Irrigation and aspiration - flush with fluid and suck fluid out.

Question 6

What is quality use of medicines?

Answer 6

Best possible use of medicines to improve health outcomes.

Question 7

What are adverse drug events?

Answer 7

Any injuries resulting from medication use.

• physical harm
• mental harm
• loss of function

Question 8

What factors contribute to the drug response?

Answer 8

Age - infants and elderly more sensitive to drug effects
Development to tolerance
Disease States- liver/kidney disease affect metabolism & elimination
Individual behaviours/beliefs
Pregnancy - altered plasma volume
Drug - drug interactions
Diet