Week 5 Flashcards

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1
Q

Med example

A

Pituatiry dwarfism,

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2
Q

How is DNA fit into the nucleus

A

Split between 23 chromosomes

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3
Q

Mitosis

A

Cell division

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4
Q

Name the 3 phases in the cell cycle

A

Interphase, M, interphase

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5
Q

What are the 3 dna sequences needed in a chromosome

A

Telomere, rep origin, centromere

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6
Q

What are nucelosome made of?

A

Histone proteins

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7
Q

How many histone proteins does each nucleosome contain

A

8

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8
Q

Where are ribosomes produced

A

Nucleoli

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9
Q

How is each unit of DNA symboliosed?

A

with a letter e.g A

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10
Q

Gene def

A

A gene can be defined as the length of DNA required to produce a given polypeptide

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11
Q

The central dogma

A

flow of info is DNA_RNA_Protein

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12
Q

RNA copies of genes are made by

A

RNA polymerase

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13
Q

Name the grooves on a double helix

A

Major and minor groove

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14
Q

Protein motifs

A

Regular combinations of secondary structures

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15
Q

Activators…

A

Boost transcription

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16
Q

Repressors…

A

Decrease transcription

17
Q

What AA does bacteria need?

A

Tryptophan, usually got by food

18
Q

What is needed to synthesise TRP

A

5 enzymes

19
Q

Operon def

A

a bacterial gene cluster controlled by a single promoter eg the Trp operon

20
Q

What is TRP operon controlled by

A

Repressor

21
Q

Eucaryotes have …

A

Linear chromosomes and uninterrupted genes

22
Q

Transcription factors

A

Refers to the proteins involved in the process of converting dna - rna, which depend on the signals in dna, genes are turned on/off by them

23
Q
A