week 5 Flashcards
There are two kinds of cells:.
prokaryotic and eukaryotic.
There are two main lineages of prokaryotes
Bacteria and Archaea.
Prokaryotes tend to be structurally _____, but are _______ and ______ very diverse.
simple
genetically
metabolically
Eukaryotic cells tend to be much _____ than prokaryotic cells and contain many internal compartments (organelles)
larger
Some of those compartments have an
endosymbiotic origin
What is an endosymbiotic origin?
they are derived from once free-living Bacteria. The key evidence is ultrastructural (the detailed cell structure of bacteria compared to the endosymbiotic organelles) and genetic (mitochondria and chloroplasts have bacteria-like genomes).
Endosymbiosis is a powerful evolutionary force.
Mitochondria are related to
Alphaproteobacteria, chloroplasts to Cyanobacteria.
Molecular phylogenetics suggests that
the host cell for the mitochondrial endosymbiont was a member of the Asgard archaea.
There are various interesting scenarios for how interactions between Asgard archaea and Alphaproteobacteria
gave rise to the first eukaryotic cells, although testing these scenarios is difficult.
What are the differences between prokaryotic and eukaryotic cells?
Prokaryotes:
–Relatively undifferentiated.
— Small; a few micrometres (0.5-5 μm) in length (e.g. Escherichia coli, 1-2μm).
- (Relatively) simple structure: a cytoplasm containing a circular DNA chromosome (the genome),
surrounded by a cell membrane and cell wall.
- Limited structural organisation of cytoplasm.
–Most (but not all) prokaryotes have simple shapes, and are a few microns
(millionths of a metre, thousanths of a milimetre) long.
Eukaryotic ---Euglena gracilis, a single-celled eukaryote (~35-80μm long, or longer) ---Large, many internal compartments. Compartments: - Nucleus (containing DNA genome on chromosomes) - Mitochondria (for oxidative phosphorylation) - Chloroplasts (photosynthesis) - Vacuoles Often other compartments, complex cell behaviours
What are the three prokaryote cell shapes?
Bacillus
Coccus
Spirillum
What are three types of harmful bacteria?
Escherichia coli: mostly friendly gut bacterium.
Staphylococcus aureus: skin and mouth bacterium.
Borellia burgdoferi: nasty spiral-shaped bacterium that causes Lyme’s disease.
What is the function of the nucleus in eukaryotic cells?
- contains the genome.
- Site of transcription (DNA
to RNA).
What is the function of the endoplasmic reticulum in eukaryotic cells?
is continuous with the nucleus: - Translation (synthesis of proteins) - Lipids - Carbohydrates
Together what is the function of the nucleus and ER in eukaryotic cells?
a membrane-bound complex for controlling the cell.
What are eukaryotes?
organisms made of eukaryotic cells.
● Most eukaryotes are single-celled; these are called protists (e.g. Euglena).
● Eukaryotes have evolved to become multicellular many times, giving rise to
animals, plants, fungi, brown algae, slime moulds, and other groups.
● Eukaryotes evolved once: all eukaryotic cells share a common ancestor.
What is symbiosis?
Symbiosis: two organisms living together for mutual benefit. Common in nature, and familiar from natural history, e.g. clownfish and anemones. The most striking cases involve co-evolution, where the partners gradually evolve to work together more effectively (clownfish-anemone host specificity). What starts off as a loose interaction between partners can evolve to become much more specific and intimate.
Symbioses among prokaryotes are
ubiquitous
How does symbioses occur in prokaryotes?
Archaea-Bacteria symbioses involve the exchange of electrons or hydrogen molecules (H2 ) over very short distances between cells. Very short distances needed for efficient exchange (vs. diffusion).
What is endosymbiosis?
one organism living inside another
In endosymbiosis, the association between the partners evolves to become so
intimate that one ends up entirely inside the other.
The endosymbiotic theory: the structural complexity of eukaryotic cells arose
from one (or more) organisms living inside another.
Those 2 organisms co-evolving for such a long time leads to a super organism thats completely integrated and where you cant really tell apart the original partners anymore.
So its a symbiosis thats evolved to such a state that you cant separate the organisms.