week 4: lipids pt 2 Flashcards

1
Q

role of digestion of lipids in mouth; stomach; liver; pancreas

A

mouth has minimal triglyceride digestion; gastric lipase in stomach has limited triglyceride digestion; liver produces bile; pancrease secretes pancreaatic lipase into small intestine

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2
Q

small intestine role in digestion of lipids (3)

A

bile action; pancreatic lipase action; micelles formed (water soluble)

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3
Q

pancreatic lipase action in small intestine

A

triglycerides broken down to monoglycerides + fatty acids

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4
Q

long chain fatty acids, monoglycerides, phospholipids and cholesterol have ____ diffusion into enterocyte - released from _____

A

passive diffusion; from micelle

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5
Q

triglycerides are packaged into ____ with phospholipids, cholesterol, fat soluble materials and proteins

A

chylomicrons

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6
Q

short/ medium chain fatty acids and glycerol have ____ diffusion directly into blood from ____

A

passive diffusion; from enterocyte

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7
Q

fatty acids that can be transported freely through the blood

A

short/ medium chain fatty acids (not in chylomicron)

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8
Q

fatty acids that need to be bound to a protein (____) in _____

A

long chain fatty acids; albumin; lipoproteins

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9
Q

chylomicrons transport triglycerides from where to where?

A

from diet/ small intestine to cells

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10
Q

VLDL transport triglycerides from where to where?

A

from liver to cells

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11
Q

which lipoprotein delivers cholesterol to most cells of the body?

A

LDL

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12
Q

high levels of ___ are related to cardiovascular disease (CVD) risk

A

LDL

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13
Q

HDL is made by the ___ and does what?

A

liver; picks up cholesterol and brings it into the liver

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14
Q

high levels of HDL related to ___ risk for CVD

A

low risk

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15
Q

good vs bad cholesterol

A

HDL vs LDL

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16
Q

lipoprotein lipase (LPL)

A

enzyme that breaks down chylomicrons and VLDL

17
Q

atherosclerosis is hardening of ___ from ____

A

hardening of arteries from buildup of plaque along arterial lining

18
Q

arteriosclerosis is the buildup of plaque in the ____

A

arterioles

19
Q

ischemia

A

lack of oxygen to tissue

20
Q

myocardial infection

A

heart attack; occlusion of blood vessels to heart and damage to tissue

21
Q

cerebrovascular accident

A

stroke

22
Q

CVD development - initiation phase

A

lesion, plaque formation, deposition of fat and cholesterol

23
Q

CVD development - progressive phase

A

thickening of plaque, promoted by high blood LDL levels. arteries become less elastic

24
Q

CVD development - termination phase

A

very narrow lumen, clot or spasm leading to complete occlusion of blood vessel = stroke

25
Q

risk factors of CVD

A

smoking, hypertension, abnormal blood lipids (fasting), diabetes, inflammation, obesity, stress, genetics

26
Q

men develop CVD ___ compared to women

A

earlier; women after menopause

27
Q

dietary strategies to reduce risk of CVD are reducing ____ fat intake and replacing it with what? helps to decrease what?

A

reduce saturated fat intake, replace saturated with mono- and poly-unsaturated fats (helps decrease LDL)

28
Q

decreasing trans fat intake help increase ___ and decrease ____

A

increase HDL and decrease LDL

29
Q

which is more important, the type or amount of fat consumed?

A

the type of fat consumed