Week 4 - Cognition, Development & Psychopathology Flashcards

1
Q

MZ correlation of g

A

.85

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2
Q

DZ correlation of g

A

.6

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3
Q

first-degree correlation of g

A

.45

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4
Q

C in g

A

.25

but disappears in adulthood

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5
Q

heritability g

A

around 60%

goes up with age

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6
Q

subscales of g and their heritability

A

heritability greater in verbal than in spatial

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7
Q

heritability and quality of environment for humans

A

the better the environment the higher the heritability

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8
Q

heritabiltiy and environment in rats

A

differences strongest in normal

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9
Q

what do teacher’s really assess

A

SES and ethnicity

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10
Q

assortative mating consequences

A

A goes down
C goes up
only for DZ

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11
Q

sibling earnings gap

A

frist borns have higher IQ
social explanation: more attention
there is also a biological one

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12
Q

missing heritabiliy

A

in GWAS
compared to twin data
the more complex a trait is the more is missing

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13
Q

endophenotype

A

easily measurable trait

seen as subscale of e.g. working memory -> IQ

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14
Q

head size

weight

A

first only C

then mostly A

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15
Q

upper bound of heritability

A

MZ correlation

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16
Q

historical theories on autism

A

refrigerator mom theory
slight brain damage
vaccinations

all wrong

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17
Q

relative risk

A

not the same as concordance

18
Q

autism heritability

A

70-80%

19
Q

ASD genetic correlations

A

negative with well-being

20
Q

liability threshold

A

relatives of diagnosed person are often subclincal

21
Q

risks for autism

A

multiple fevers in pregnancy

childhood toxin exposure e. g. lead

22
Q

ADHD heritability

A

70%

23
Q

ADHD correlates

A

positive with body size and smoking

negative with cognition

24
Q

smoking heritability females

A

46%

25
Q

indirect influence in smoking

A

the genes

26
Q

direct influence in smoking

A

the cigarette

27
Q

therapy with highly heritable disorders

A

family intervention is better

28
Q

therapy for stable heritability

A

the earlier the better

29
Q

assortative mating effect

A

higher C
lower A
but no higher rMZ

30
Q

environment for rats

A

poor is damaging to bright and dull
enriched improved dulls
difference between dull and bright mostly in normal

31
Q

school achievement heritability

A

highly heritable and stable

32
Q

moderate cogntiive disability

A

between 35 and 50 IQ

33
Q

three classic small chromosomal deletions

A

Prader-Willi syndrome
Williams syndrome
Angelman syndrome

34
Q

families and cognitive impairment

A

mild is familial

severe not

35
Q

most common cognitive disability

A

fragile X syndrome

36
Q

Klinefelter syndrome

A

XXY

37
Q

stability of heritability of ADHD

A

remains stable

38
Q

heritability of anxiety disorder over life

A

decreases

39
Q

autism and chromosomes

A

probably not X linked

40
Q

Angelman syndrome

A

deletion in chromosome 15 from egg cell

41
Q

Prader-Willi syndrome

A

deletion in chromosome 15 from sperm cell