Week 2 - Nature & Nurture Flashcards
Mendel’s 1st law
law of segregations
alleles are carried seperately
Mendel’s 2nd law
independent assortment
traits are inherited independent from each other
X-linked disorder
prevalence in males much higher
but not exclusive
polygenetic traits
thousand of genes
a complex trait
normally distributed
doesn’t follow Mendel’s laws
first adoption study
adopted children of biological mothers with schizophrenia
10% affected as well
none of the children of normal mothers
limitations of adoption studies
less adoption nowadays
non-representative samples and selective placement
prenatal environmental influence
open adoption
difference in MZ twins
.8% due to mutations and recombination
increase of twinning
mostly higher age of mothers
some influence by artificial fertilisation, but less so by now
amardillo
always gets identical quadruplet
rMZ
= MZ concordance
= A + C
rDZ
= DZ concordance
= 1/2 A + C
E
= unique environment
= 1 - rMZ
C
= common / shared environment
= (2 * rDZ) - rMZ
A
= additive genetic influence
= heritability
= (rMZ - rDZ) * 2
adoption design formula
(1/2 A + C) vs C