Week 3 - Skeletal system Flashcards
What is Bone made up of?
Bone is connective tissue.
Composition of the bone matrix is called osteoid.
- collagen
What is collagen?
produced by osteoblasts
* gives bone tensile strength by resisting stretching
* contributes to bone flexibility
Functions of Bones
- support of the body
- protection of soft organs
- movement due to attached skeletal muscles
- storage of minerals and fats
- blood cell formation
Compact Bone
- forms outer, hard shell of the bone
- provides solid attachments for muscles, tendons, ligaments
- organised into osteons
Spongy Bone
- porous lattice of rods and plates called trabeculae
- sponge like appearance; spaces are filled with red bone marrow and blood vessels
- imparts strength without adding too much weight
Structure of a long bone
- diaphysis (shaft)
- epiphyses
- periosteum
- endosteum
- articular cartilage
Diaphysis (shaft)
- compact bone collar surrounds medullary (marrow) cavity
- medullary cavity in adults contains fat (yellow marrow)
Epiphyses
- expanded ends
- spongy bone interior
- epiphyseal plate
- articular cartilage on joint surfaces
The periosteum
- outer fibrous layer
- inner osteogenic layer
- contains osteoblasts and osteoclasts
Endosteum
- delicate membrane on internal surfaces of bone
- also contains osteoblasts and osteoclasts
Articular cartilage
- covers the external surfacce of the epiphyses
- made of hyaline cartilage
- decreases friction at joint surfaces
Role of vitamin D
- Vitamin D is essential for maintenance of bone mineralisation through regulation of calcium and phosphorus homeostasis
- vitamin D is important for normal bone development and maintenance
microscopic anatomy of bone
- osteon
- central canal
- perforating canal
**Developmental aspects of the skeletal system **
- at birth, the skull bones are incomplete
- bones are joined by fibrous membranes - fontanelles
- fontanelles are completely replaced with bone within 2 years after birth
The pectoral girdle (shoulder)
composed of 2 bones
1. clavicle - collarbone
2. scapula - shoulder blade
allow the upper limb to have free movement
Hand Bones
- carpals - wrist
- metacarpals - palm
- phalanges - fingers
functions of Joints
- hold bones together
- allow for mobility
**classification of joints **
- fibrous joints - genrally immovable
- cartilaginous joints - immovable or slightly moveable
- synovial joints - freely moveable
types of synovial joints
- ball and socket
- pivot
- saddle
- hinge
- gliding
- condylar
inflammatory conditions associated with joints
- osteoarthritis
- rheumatoid arthritis
- gouty arthritis
Osteoarthritis
- most common chronic arthritis
- probably related to normal aging processes
Rheumatoid Arthritis
- an autoimmune disease - the immmune system attacks joints
- symptoms begin with bilateral imflammation of certain joints
gouty arthritis
- inflammation of joints is caused by a deposition of urate crystals from the blood
- can usually be controlled with diet