Week 3: Neuro Flashcards

1
Q

Migraine: Presentation

A

Pulsatile, unilateral
With or without aura
N/V, visual changes, photophobia, phonophobia
repeated attacks lasting 4-72 hours

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

Tension headaches: Presentation

A

Persistent for weeks- months

Band squeezing

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

Cluster headaches: Presentation

A

pain behind the eye

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

Sinus headaches: Clinical presentation

A

Worsens with changes in atmospheric pressure

Pain behind the forehead/cheekbones

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

Headache red flags

A
Interrupts sleep
Awakens patient
New onset > 50 y.o or < 5 y.o
Thunderclap
Focal neuro signs
Fever and headache (meningitis)
First/worst headache of life 
Change in mental status
Papilledema
Neck stiffness
Retractable vomiting
Headache that increases in frequency and severity over a period of several weeks
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

What are the headache screening questions?

A

How often do you get severe HA (difficulty to function)
How often do you get mild HA?
How often do you take pain relievers for HA?
Has there been any recent change in your HA?

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

Imaging criteria for headaches

A

Worst headache of their life
Unexplained abnormal exam finding w/ non-acute HA pattern
Recent change in pattern, frequency, severity
Progressive worsening despite appropriate tx
Onset w/ exertion, cough or sexual activity
Onset after age 40
Thunderclap headache

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

What is abortive vs. preventative treatment for migraines?

A
Preventative
- Anticonvulsants (Topamax)
- Ca channel blocker/Beta Blocker
- TCA or SSRI (if sleep interrupted) 
Abortive
- Tylenol, Excedrin, NSAIDS
- Triptans
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

What are the types of concussions?

A

Simple: sx resolve in 7-10 days w/o complication

Complex: prolonged healing beyond 10 days; sx may include those that recur w/ exertion; may have prolonged impairment of cognitive function, more common in repeat concussions

Second-impact syndrome: pt sustains second head injury before sx from the first are resolved; can cause cerebral edema and herniation, possibly death

Repetitive injury syndrome: sustains multiple concussions even when sx of prior concussions have resolved - may lead to long term neuro and functional
deficits

Post-concussive syndrome: sequela of minor head injury

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

Concussion red flags for ED referral

A
Weakness, numbness, decreased coordination
Worsening HA
Repeated N/V
Slurred speech
Anisocoria
Seizures
Inability to wake or seem very drowsy
Increasing confusion, agitation, restlessness
Focal neuro signs
Can't recognize people or places
Neck pain/nuchal rigidity
Unusual behavior changes
Any LOC esp if for 30 seconds +
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

When is it ok to dc a child w/ head injury home?

A

No loss of consciousness

OR

Loss of consciousness < 5 minutes and normal neuro exam, no s/s basilar fracture or increased ICP, AND NORMAL CT

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

Immediate referral for head injuries + ___

A

alteration in LOC, paralysis, paresthesia, rhinorrhea (glucose + on dipstick), racoon sign, battle sign, otorrhea,

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

Bell’s Palsy: Patho & causative agent

A

P: Acute paralysis of the 7th CN
C: Most commonly caused by HSV; other: CMV, EBV, adenovirus, rubella, HiB, coxsackie, pregnancy

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

Bell’s Palsy: Presentation

A
Acute unilateral upper and lower facial weakness or paralysis of CNVII with onset less than 72 hours and unknown etiology
o	Weakness of the facial muscles
o	Hyperacusis
o	Posterior auricular pain
o	Decreased tearing
o	Incomplete eyelid closure
o	Taste disturbances
o	Otalgia
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

What is the grading system for Bell’s Palsy?

A

House & Brackmann (Grade I no paralysis - VI full paralysis)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

What is a distinguishing feature of Ramsey Hunt Syndrome?

A

Rash/vesicles present

17
Q

What is crucial to r/o when assessing for Bell’s Palsy?

A

STROKE

18
Q

What else might be important to consider in dx for Bell’s Palsy?

A

Lyme titer
MRI
EEG

19
Q

Bell’s Palsy: Management

A

Protect eye due to incomplete lid closure, keep moist
Corticosteroids w/in 72 hours of onset
Antivirals can be considered (acyclovir, valacyclovir)

20
Q

What are characteristics of an epileptic seizure?

A
LOC w/ generalized motor activity
Eyes open
Mouth open
Tongue bite on the lateral edges
No response to painful stimuli
Episode short lived
21
Q

What are characteristics of a NON-epileptic seizure?

A
Preservation of consciousness
eyes closed
mouth closed
tongue bite on the tip of the tongue
normal response to painful stimuli
wax and wane for hours
22
Q

What are the characteristics of West’s Syndrome?

A

Dramatic rapid tonic contract of the trunk and limbs

Appears in 1st yr of life and diminish and disappear by 4-5

Infantile spasms + EEG pattern of hypoarrhythmia and developmental delay

23
Q

What are other seizure disorders that can occur in neonates?

A

Benign familial neonatal seizures
Early myoclonic encephalopathy
Ohtahara syndrome
Migrating partial seizures of infancy

24
Q

What are some seizure disorders that can occur in infants?

A
Aicardi's syndrome
Benign myoclonic epilepsy of infancy
Benign infantile seizures
Dravet syndrome
West's syndrome
25
Q

What are some seizure disorders that can occur in children?

A
Benign Rolandic epilepsy
Lennox-gastaut syndrome
Landau-kleffner syndrome
Childhood absence epilepsy
Progressive myoclonic
26
Q

What are some seizure disorders that can occur in adolescents?

A

Idiopathic generalized epilepsies
Juvenile myoclonic epilepsy
Reflex epilepsies

27
Q

What are characteristics of Lennox-gastaut syndrome?

A

Multiple seizure types: tonic and atonic seizures, may also include absence and myoclonic seizures and non-convulsive SE
Developmental delay or regression w/ or w/o other neuro abnormalities

28
Q

What are the characteristics of childhood absence epilepsy?

A
  • 8% of epilepsy in school aged children
  • Girls are 60-78%
  • Peak incidence 6-7 yo
  • Occurs in developmentally normal children
  • Brief seizures; misdiagnosed with ADHD
  • Occurs frequently - 10-100 times per day
  • May see eye fluttering, eyes rolling upwards, lip smacking, autonomic sx (flushing, tachycardia)
29
Q

What is the general approach to management of new-onset seizure disorder?

A

Referral to neurology and can monitor once treatment initiated

30
Q

What is an important consideration for female patients with seizure disorders?

A
  • OCP needs to contain at least 50mcg of estrogen to overcome the interaction with AEDs
  • Decreased efficacy of morning after pill
  • Folate may need to be increased as AED can effect absorption
  • Refer any woman who is considering pregnancy on AEDs
31
Q

MS: clinical presentation

A

visual disturbances, weakness of the limbs, facial paralysis, vertigo, coordination issues, tremors, pain w/ movement, bowel & bladder dysfunction

32
Q

MS: what patient population does it more frequently affect?

A

women between 20-50 yo

33
Q

MS: management?

A

MRI - neuro and MS specialist referral for initial evaluation and can manage treatment plan from there