Week 3- Intro to biologics and anti-TNF Flashcards
1
Q
which section of the antibody is the constant region?
A
bottom part
2
Q
which section of the antibody is the variable region?
A
top part
3
Q
what are the 2 types of TNF receptors?
A
TNF1 or TNF2
4
Q
what is the role for TNF?
A
-it is a cytokine and its role is involved in inflammation and autoimmune diseases leading to apoptosis
5
Q
how does TNF signal?
A
through transcription factors like NFkB and be a growth factor
