Week 3- Drugs used in immune disease

Question 1

what are the different types of biologic agents used for immune disease?

Answer 1

• anti-TNF
• IL-6 receptor inhibitor
• anti-B cell
• anti-T cell
• JAK inhibiros

Question 2

what is infliximab?

Answer 2

• it is a TNF inhibitor
• used for rheumatoid arthritis, CD and UC, psoriasis
• its a human monoclonal antibody

Question 3

what are some of the side effects for infliximab?

Answer 3

-Very common – infection (upper respiratory infection), headache, infusion
related reaction, pain
-Most serious – serious infections and reactivations, new or worsening HF,
delayed hypersensitivity, haematological reactions, demyelinating
disorders, hepatobiliary events, malignancies, serious infusion reactions