Week 3 - Immunology Flashcards
A foreign substance that stimulates immune response and generates antibody production
Antigen
Specific protein produces in humoral response to bind with an antigen
Antibody
A gland located in the superior mediastinum, site of maturation of T lymphocytes
Thymus
Contains many lymphocytes, filter body fluids, remove foreign matter, generates immune response
Lymph Nodes
Disorders resulting from an overactive immune system that fails to recognise ‘self’
Autoimmune disease
Specialised lymphocytes produced and matured in bone marrow, are precursor to plasma and memory cells
B Lymphocytes
Specialised lymphocytes produced by the bone marrow and matured in thymus, which is responsible for cell-mediated immunity
T Lymphocytes
WBC’s for phagocytosis; innate defence; active in inflammation
Neutrophils
WBC’s; bind IgE, release histamines
Basophils
WBC’s; participate in allergic responses and defence against parasites
Eosinophils
WBC’s; migrate from the blood into tissues to become macrophages
Monocytes
Phagocytes; process and present antigens to lymphocytes for the immune response
Macrophages
Found within connective tissue, release chemical mediators such as histamines
Mast Cells
Develop from B lymphocytes to produce and secrete antibodies
Plasma Cells
Destroy antigens, cancer cells, virus cells
Cytotoxic T Cells