week 3 Flashcards
what is respiratory failure
respiratory failure occurs when the respiratory system fails top oxygenate arterial blood adequately (hypoxaemia) and consequently fails to provide the body with adequate amounts of oxygen (hypoxia) and/or the person fails to ventilate well enough to eliminate carbon dioxide
what is hypoxia
inability to provide oxygen to the tissues
what is hypoxaemia
lack of oxygen in arterial blood
How do we diagnose respiratory failure
take a sample of arterial blood and measure the partial pressure of O2 and CO2
what are the two main types of respiratory failure
type 1 and type 2
how long does it take for acute respiratory failure to develop
minutes to hours
whats an example of an acute respiratory failure
pneumonia
how long does chronic respiratory failure take to develop
over days
what is an example of chronic respiratory failure
COPD
what is type 1 respiratory failure
failure to maintain O2 levels in arterial blood
(hypoxaemia)
what is type 2 respiratory failure
failure of respiratory pump to ventilate adequately
(hypoxaemia and hypercapnia)
what is ischaemic hypoxaemia due to
inadequate blood flow through the lung
What is anaemic hypoxaemia
reduction in the carrying capacity of the blood e.g. anaemia/significant blood loss/sickle cell crisis
what is toxic hypoxaemia
difficulty utilising oxygen
what are some of the clinical signs of hypoxaemia
central cyanosis
peripheral shut down (cool to touch, cold and clammy)
tachypnoea
tachycardia
low oxygen saturations
confusion or agitation
Causes of type 2 respiratory failure
CNS depression/abnormalities with the respiratory drive centres
disorders of the spinal cord
abnormalities of the peripheral nerves
respiratory disease
neuromuscular disease
muscle weakness
loss of integrity of the chest wall/poor ventilatory mechanics
what can happen if patients with hypoxic drive are given large and unchecked amounts of additional oxygen
it can remove their drive to breathe
what is hypoxic drive
a condition associated with a small number of people with COPd and tends to be associated with more severe cases