Week 2 Reading Quiz: Class 3 Flashcards
The infectious cycle includes steps that are common to ALL virus reproduction cycles. Which of the following are steps in the infectious cycle?
a
Genome replication
b
Assembly
c
Release
d
Attachment & Entry
e
Translation
f
All of the above
All of the above
Cells must be both susceptible and permissive if an infection is to be successful
a
TRUE
b
FALSE
TRUE
How do scientists cultivate (grow) viruses?
Select an answer and submit.
a
Cell culture
b
Laboratory animals
c
Embryonated eggs
d
A-C
e
None of the above
D. A-C
Cell culture
Laboratory Animals
Embryonated eggs
Which of the following cytopathic effects would be visible by conventional light microscopy?
a
Rounding up and detachment of cells from culture dish
b
Cell lysis
c
Swelling of nuclei
d
Syncytium formation.
e
Assembly of individual viral components in cellular compartments.
f
A-D
g
A-E
F. A-D
On average, how long does it take to make a vaccine in chicken eggs ( from time egg is delivered to facility to being delivered to customer)?
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a
1 month
b
3 months
c
4 months
d
6 months
e
1 year
d. 6 months
Who was Henrietta Lacks and why was she significant?
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a
A hispanic woman who died in the early 1950s from cancer and whose cells provided the world’s first and still widely used continuous cell line.
b
A caucasian woman who died in the early 1950s from cancer and whose cells provided the world’s first and still widely used continuous cell line.
c
An African American woman who died in the early 1950s from cancer and whose cells provided the world’s first and still widely used continuous cell line.
c
An African American woman who died in the early 1950s from cancer and whose cells provided the world’s first and still widely used continuous cell line.
What vaccine was tested in HeLa cells by Jonas Salk in the 1950s?
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a
Influenza
b
Polio
c
HIV
d
Ebola
e
Smallpox
b. Polio
A single reproduction cycle that occurs synchronously in every infected cell.
One-step growth curve
The sum total of all events that occur during the infectious cycle.
Virus reproduction
Providing the receptor(s) required for virus entry; refers to cell
Susceptible
Able to support virus reproduction when viral nucleic acid is introduced; refers to cells.
Permissive
A layer of cultured cells growing in a cell culture dish
Monolayer
Cell cultures are prepared from animal tissues; these cultures include several cell types and have a limited life span usually no more than 5 to 20 cell divisions.
Primary cell cultures
Cultures of a single cell type that can be propagated indefinitely in culture.
Continuous cell lines
The morphological changes induced in cells by viral infection
Cytopathic effects
