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Pharmacology > Week 2 Med Cards > Flashcards

Week 2 Med Cards Flashcards

1
Q

Penicillin is what?

A

Antibiotic

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2
Q

Penicillin side effects?

A 
N/V/D
Superinfection
Rash, fever, etc. (anaphylaxis)
Black, hairy tongue
Hyperkalemia 
Hypersensitivity
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3
Q

Penicillin: interactions with other drugs

A

Tetracylines, aminoglycosides given in same parenteral route

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4
Q

Penicillin: antidote

A

Epinephrine, antihistamines, and steroids for allergies

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5
Q

Penicillin: what would you give it for?

A

Strep and staph infections

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6
Q

What should you assess for before giving penicillin?

A

Hx of renal disease

Hx of carbapenem, cephalosporin or penicillin allergies

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7
Q

What do you monitor while someone is taking penicillin?

A

Creatinine, BUN, and resistant or opportunistic infections

  • WBC, temp., site of infection
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8
Q

How do you administer penicillin?

A

PO, IV, or IM depending on the type of penicillin

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9
Q

What is tetracycline?

A

Antibiotics

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10
Q

What does tetracycline treat?

A

E. Coli, chlamydia, Klebisella

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11
Q

How do you administer tetracycline?

A

PO

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12
Q

What should you be aware of before giving someone tetracycline?

A

Hx of bone marrow problems, hyperparathyroid or bone problems

Pregnancy, lactating, or children under 8 y/o

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13
Q

What does tetracycline interact with?

A

Oral contraceptives
Pencillin G (decreases effectiveness)
Digoxin

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14
Q

What are side of effects of tetracycline?

A

Tooth and bone damage
Bone marrow suppression
Photosensitivity

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15
Q

What is tobramycin?

A

Antibiotic

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16
Q

What does tobramycin treat?

A

Bacterial infections susceptible to penicillins

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17
Q

tobramycin administration rought

A

IV

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18
Q

What do you monitor for when someone is taking tobramycin

A

Urine output 2mL/kg/hr
Creatinine
Tinnitus

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19
Q

tobramycin interactions

A

Synergistic with Cephalosporin or penicillins, but cannot be given with penicillins same IV bag.

Diuretics can increase toxicity.

Neuromuscular blockers increase duration of paralysis one given with aminoglycosides

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20
Q

tobramycin side effects

A 
Nephrotoxic 
Ototoxicity
Bone marrow suppression
GI upset
Decreased urine output
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21
Q

When giving tobramycin, what patients should you monitor closely?

A

Hx of renal disease
Hx hearing loss
Hx of myasthenia

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22
Q

Metronidazole is what?

A

Antiprotozoal

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23
Q

How is Metronidazole administered?

A

IV

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24
Q

Why is Metronidazole narrowly used?

A

Confirmed sensitivity test due to emerging resistance

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25
Q

When giving Metronidazole, what patients should be monitored closely?

A

Hx allergy to carbapenems or penicillins

Hx pregnancy

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26
Q

Metronidazole interactions

A

Animoglycosides (toxicity)

Serious ETOH toxicity

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27
Q

Metronidazole side effects

A

Bleeding risk
HA
Dizziness
Phlebitis

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28
Q

What is Aztreonam?

A

Mono-antibiotic

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29
Q

What do you use Aztreonam to treat

A

Gram positive enterobacteria

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30
Q

Aztreonam administration route

A

IV, IM, inhalant

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31
Q

When giving Aztreonam, what patients should you closely monitor?

A

Elderly
Hx renal insufficiency
Hx liver disease (monitor liver enzymes, GI problems and injection pain)

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32
Q

Aztreonam interactions

A

Aminoglycosides

Cefoxitin

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33
Q

Aztreonam side effects

A

Sz
Hypotension
N/V/D

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34
Q

Clarithromycin is what?

A

Antibiotic

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35
Q

What can you give Clarithromycin to treat?

A

Strep

H. Pylori

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36
Q

Clarithromycin side effects

A

GI upset
QT prolongation
Hepatic metabolism inhibition

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37
Q

Clarithromycin interactions

A

Alfa is in
Atazanavir
Carbamazepine

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38
Q

What patients should you monitor if they are taking Clarithromycin

A

Hx cardiac problems

Hx allergy

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39
Q

What physiologic functions should you monitor while any patient is taking Clarithromycin ?

A

Metabolic enzymes of liver
INR
QT prolongation

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40
Q

Ciprofloxacin is what

A

Antibiotic

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41
Q

Ciprofloxacin is used to treat what

A

Sinusitis, bronchitis and UTI

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42
Q

Ciprofloxacin administration route

A

PO or IV

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43
Q

Ciprofloxacin interactions

A

Theophylline (increases half-life)
Cyclosporine (toxicity)
Steroids (increase risk of tendinitis)
St. John’s wort

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44
Q

Ciprofloxacin side effects

A

Sz
HA
Pseudomembranous colitis tendinitis and tendon rupture risk

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45
Q

Ciprofloxacin teaching considerations

A

Sun exposure and protection

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46
Q

What should you monitor if they are taking Ciprofloxacin

A 
Hx liver disease
Hx muscle weakness / muscle pain/spasms
Liver enzymes
Calcium levels
CNS
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47
Q

Clindamycin is a what?

A

Antibiotic (lincosamide)

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48
Q

What do you treat with Clindamycin?

A

Anaerobes, streptococci, and PID causing bacteria

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49
Q

How do you administer Clindamycin?

A

PO or topically

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50
Q

What are signs you should monitor for when someone is taking Clindamycin?

A

Signs of superinfection and skin color changes

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51
Q

What does Clindamycin have a cross sensitivity to?

A

Lincomycin

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52
Q

What interactions does Clindamycin have with other meds?

A

Lincomycin and erythromycin

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53
Q

Side effects of Clindamycin

A

N/V/D
Superinfection
Join pain/swelling

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54
Q

Linezolid is what?

A

Antibiotic

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55
Q

How do you administer linezolid?

A

IV, injection, PO (suspension)

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56
Q

What interactions should you keep in mind when giving someone linezolid?

A

Adrenergic, insulin, seratonergic

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57
Q

What are you treating if you are giving someone linezolid?

A

Vancomycin-resistant bacteria, hospital acquired staph infections, other skin conditions (uncomplicated)

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58
Q

What should you monitor when treating someone with linezolid? (Side effects)

A

CBC, leukocyte differential, skin irritations (indicates super infection)

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59
Q

What is tenofovir?

A

Antiretroviral

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60
Q

What does tenofovir interact negatively with?

A

Atazanvir, boceprevir, didanosine

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61
Q

What does tenofovir treat?

A

HBV, HIV-1

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62
Q

Who should you monitor when giving someone tenofovir?

A

Contraindicated <2 y/o (non prophylactic at birth)
Lactating mother’s
People with osteoporosis

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63
Q

tenofovir administration

A

PO

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64
Q

tenofovir side effects

A 
HA
Depression
Insomnia 
Flu-like s/s 
Nephrotoxicity (creatinine)
Hepatotoxicity (liver enzymes)
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65
Q

What is Efavirenz

A

Antiretroviral

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66
Q

What does Efavirenz treat

A

HIV

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67
Q

Efavirenz administration

A

PO

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68
Q

Efavirenz interactions

A

Amprenavir
Clarithromycin
Bupropion

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69
Q

Efavirenz side effects

A

N/V/D (flu like symptoms)
Dizziness
Rash / lesions

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70
Q

What should you monitor when someone is taking Efavirenz?

A

LFT
Psychiatric changes
ECG for possible QT changes
Liver functions

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71
Q

What is Trimethoprim / sulfamethoxazole?

A

Antibiotic

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72
Q

What do you use Trimethoprim / sulfamethoxazole to treat?

A

UTI, STI, RA

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73
Q

Trimethoprim / sulfamethoxazole administration

A

PO

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74
Q

Trimethoprim / sulfamethoxazole interactions

A

Cyclosporine
Digoxin toxicity
Sulfonyluea (will increase hypoglycemia)

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75
Q

What should you monitor if someone is taking Trimethoprim / sulfamethoxazole?

A 
Someone with hx of thrombocytopenia
Infants younger than 2mo 
RFT
CBC
LFT
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76
Q

Trimethoprim / sulfamethoxazole side effects

A

Sz.
Thrombophlebitis
Pancrease

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77
Q

Acyclovir is what

A

Antiviral

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78
Q

What does acyclovir treat?

A

HSV
Varicella zoster
Herpes

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79
Q

Acyclovir administration

A

PO
Buccal
IV
Topical

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80
Q

Which patients should you monitor closely if they are taking acyclovir?

A

Hx neurological problems

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81
Q

acyclovir interactions

A

Varicella vaccine may be diminished
Probenecid
Foscarnet (nephrotoxicity)

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82
Q

acyclovir side effects

A 
HA
Malaise
N/V/D
GI upset
Nephrotoxicity
Fatigue
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83
Q

Amphotericin B is what

A

Antifungal

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84
Q

Amphotericin B interactions

A

Antineoplastics, cardiac glycosides, cyclosporine

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85
Q

Amphotericin B - things / people to monitor

A

Hx renal failure, elderly, pregnant women
Watch all electrolytes, creatinine, liver enzymes

Several toxic

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86
Q

Amphotericin B administration

A

IV

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87
Q

What does Amphotericin B treat?

A

Systemic fungal infections, sometimes in the immunocompromised

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88
Q

Amphotericin B side effects

A

Fever
CP
Anemia
Hematuria

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89
Q

Fluconazole is what?

A

Antifungal

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90
Q

Fluconazole administration

A

PO

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91
Q

What does Fluconazole treat?

A

Candidiasis infections and fungal meningitis

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92
Q

Fluconazole interactions

A

PMS medications

Medications that prolong QT (clarithromycin)

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93
Q

What patients should be monitored closely if they are taking Fluconazole?

A

Those with hx of pregnancy, lactation, hepatic disease, QT prolongnation

Monitor LFT

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94
Q

Fluconazole side effects

A

Hepatotoxicity
HA
Dizziness

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95
Q

What is Nitrofurantoin?

A

?

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96
Q

Nitrofurantoin - what should you assess / monitor closely

A

Children less than one month of age
Allergies
History of blood disorders, kidney or liver disease
Diabetes

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97
Q

What does Nitrofurantoin treat?

A

UTI

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98
Q

Nitrofurantoin administration

A

Oral

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99
Q

What should be monitored while taking Nitrofurantoin?

A

Those pregnant, with poor kidney functions as well as electrolytes

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100
Q

Nitrofurantoin interactions

A

Urine glucose tests

Sulfinpyrazone

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101
Q

Nitrofurantoin side effects

A

Nausea
Peripheral neuropathy
Sz
Dark urine

102
Q

What is Oseltamivir ?

A

?

103
Q

What does Oseltamivir treat?

A

Influenza

104
Q

Oseltamivir administration

A

Oral

105
Q

Oseltamivir interactions

A

Flue vaccine

106
Q

Oseltamivir side effects

A

N/V
Mental/mood changes (esp. kids)
Nephrotoxicity

107
Q

What should you be evaluating when someone is taking Oseltamivir?

A

Kidney function
Worsened or new side effects
Cough, sore throat, fever
Urine output

108
Q

When is it best to take Oseltamivir

A

< 48 hours after onset of flu symptoms

109
Q

What is vancomycin?

A

?

110
Q

vancomycin administration

A

Oral, generally IV

111
Q

vancomycin interactions

A

Cholestol medication

112
Q

What does vancomycin treat?

A

Colitis

113
Q

What should you be monitoring when someone is taking vancomycin?

A

Diarrhea
Peak / trough
Urine output
Growth of bacteria / stool

114
Q

vancomycin side effects

A

Nephrotoxicity
Ototoxicity
Easy bruising / bleeding

115
Q

What are examples of penicillin

A

Amoxicillin

Piperacillin / tazobactam

116
Q

What should you do before prescribing penicillin?

A

Culture before first dose

117
Q

What should be in the patients stomach before giving penicillin

A

Nothing

Can take with water - no acid juices (will impede absorption)

118
Q

What does penicillin decrease the effectiveness of?

A

Oral contraceptives

119
Q

Cephalosporins are what

A

Antibacterial

120
Q

What are examples of cephalosporins?

A

Cephalexin
Cefazolin
Ceftriaxone
Cefepime

Start with “ceph/cef”

121
Q

Cephalosporins have a cross sensitivity to what

A

Penicillin

122
Q

What reaction can you expect if you drink alcohol while taking a cephalosporin?

A

Disulfiram reaction - you get really really sick

123
Q

Why might you want to drink a lot of water while taking cephalosporins

A

They can be nephrotoxic. Drinking fluids washes the medicine out of the kidneys so it isn’t harming the kidneys

124
Q

Antibiotics interfere with what

A

Anticoagulation

125
Q

Cephalosporin side effects

A

N/V/D
Nephrotoxicity
INR (can elevate)
Hemolytic anemia

126
Q

Does it matter if you have food in your stomach when you take cephalosporins?

A

Absorption is not impacted whether or not you have food in your stomach - can take with food

127
Q

What disorder should you be cautious about when giving someone cephalosporins

A

Use in caution to seizure disorder

128
Q

What do you want to monitor when giving someone cephalosporins

A

BUN and creatinine and urine output (if urine output is low, call provider)

S/s of infection

Culture results

129
Q

Antibiotics interfere / have negative reactions with what

A

Alcohol, anticoagulation, oral contraception

130
Q

What are carbapenems?

A

Antibiotics

131
Q

What is an example of carbapenems

A

Imipenem

132
Q

carbapenems administration

A

IV only

133
Q

carbapenems cross sensitivities

A

Penicillin and cephalosporins

134
Q

Use caution when giving carbapenems with what disorders?

A

Seizure disorder or renal impairment

135
Q

carbapenems side effects

A

N/V/D
Elevated INR
Hemolytic anemia

136
Q

A normal INR is less than what

A

Less than 1 (double check this)

137
Q

Monobactams are what

A

Narrow spectrum antibiotics

138
Q

Monobactams cross sensitivities

A

Penicillin
Cephalosporins
Carbapenems

139
Q

Monobactams administration

A

IM
IV
Inhalation

140
Q

Monobactams side effects

A

N/V/D
Nephrotoxicity
Elevated INR
Hemolytic anemia

141
Q

What is an example of a Monobactam

A

Azetreonam

142
Q

Sulfonamides are

A

Antibiotic

143
Q

What are examples of sulfonamides

A

Trimethoprim-sulfamethoxazole (synergistic)

144
Q

sulfonamides have what in the name

A

Sulf

145
Q

sulfonamide side effects

A 
Rash (discontinue)
Photosensitivity
Crystalluria 
Nephrotoxic 
Bruising
146
Q

Why do you want to monitor UOP with sulfonamides

A

Can cause kidney stones

147
Q

sulfonamides interactions

A

Sulfonylureas (meds that are used to lower blood pressure)

Cardiac arrhythmic meds

148
Q

What should you take sulfonamides with

A

Full glass of h2o

149
Q

If someone is allergic to sulfonamides, they are also allergic to what

A

Sulfonylureas

150
Q

What are fluoroquinolones

A

Antibiotics

151
Q

What are examples of fluoroquinolones?

A

Levofloxacin

Ciproflaxin

152
Q

Most fluoroquinolones are what

A

Broad spectrum

153
Q

Ciproflaxin is used for what

A

Anthrax

154
Q

fluoroquinolones side effects

A 
GI upset
Hypersensitivity
Photosensitivity 
Hypoglycemia 
C. Diff
155
Q

fluoroquinolones - what should you have in stomach

A

Nothing

Take full glass of water 2 hours after meals

156
Q

When taking fluoroquinolones, you should avoid meals with what?

A

Calcium, aluminum, iron or zinc (will impeded absorption)

157
Q

What people should you be cautious of / monitor patients when taking fluoroquinolones

A

Children (contraindicated)

Hx seizures

158
Q

fluoroquinolones prolongs what in ECG

A

QT segment (ventricular relaxation ?)

159
Q

fluoroquinolones: black box warning with what

A 
Tendinitis and tendon rupture (esp. young boys) 
Peripheral neuropathy (lack of feeling / inflammation)
CNS effects (HA / dizzy)
160
Q

Macrolides are what?

A

Antibiotics

161
Q

Macrolides: examples

A

Erythromycin

Azithromycin

162
Q

Macrolides: side effects

A 
GI upset
Hypersensitivity
Photosensitivity
Hepatotoxicity
Onset / worsening of myasthenia 
Drowsiness 
QT prolongation 
Dysrhythmias
163
Q

What should be in your stomach with Macrolides

A

Take with FOOD

164
Q

What lab values do you want to monitor with hepatotoxic drugs

A

AST and ALT

165
Q

Aminoglycosides are what?

A

Antibiotics

166
Q

Aminoglycosides examples

A

Streptomycin

Gentamycin

167
Q

Aminoglycosides side effects

A

GI upset
Rash
Respiratory paralysis if given too soon after neuromuscular blocking medication
Can cause harm to fetus and breast fed infants (teratogenic)
Neurotoxic (HA, dizzy, sz.)
Nephrotoxicity
Ototoxic

168
Q

What do you want to monitor when giving someone Aminoglycosides

A

Peak and trough

169
Q

Tetracycline is what

A

Antibiotic

170
Q

Tetracycline side effects

A

GI upset
C. Diff
Permanent teeth discoloration / enamel hypoplasia if given to under 8 y/o
Intracranial hypertension (HA, blurred vision, vision loss, diplopia)
Photosensitivity

171
Q

What should you not take while on Tetracycline

A

Oral contraception

172
Q

What are three instances in which you would NOT want to take Tetracycline

A

Pregnant
If its expired (toxic)
With calcium

173
Q

What is a common problem with patience who take acyclovir

A

Medication compliance

174
Q

Can you take acyclovir with food

A

Yes

175
Q

Oseltamivir is what

A

Anti-viral

Anti-influenza

176
Q

What does oseltamivir do

A

Shortens duration and decreases s/s of influenza within 48 hours of onset

177
Q

oseltamivir side effects

A

GI upset
Neuropsych
Fatigue
Nephrotoxicity

178
Q

You should use oseltamivir cautiously with what

A

Cardiac or respiratory disease

179
Q

oseltamivir can be used _____

A

Prophylactically

180
Q

Adefovir is what

A

Antiviral (anti hepatitis)

181
Q

How long does Adefovir therapy last

A

Prolonged >1 year

182
Q

Adefovir therapeutic effects

A

Maintain or improve liver function when active disease is present

183
Q

Adefovir side effects

A

Severe or acute exacerbation of Hep. B
Nephrotoxicity
Lactic acidosis
Severe hepatomegaly

184
Q

Hepatotoxic therapy requires what

A

LFTs monitored after the therapy is complete

185
Q

Lamivudine-zidovudine is what

A

Antiviral (anti-retro viral)

186
Q

Lamivudine-zidovudine: therapeutic effects

A

Decreases changes of developing AIDS and HIV related illnesses (infections, cancers)

187
Q

Lamivudine-zidovudine side effects

A 
Lactic acidosis 
Pancreatitis 
Severe hepatomegaly  
Nephrotoxicity 
Fatigue 
Hepatotoxicity
188
Q

What are downsides to taking Lamivudine-zidovudine

A

Compliance

Prolonged therapy

189
Q

Mycoses

A

Illness caused by fungi

190
Q

Characteristics of fungus

A

Opportunistic
Decompose in the environment
Critical for food (cheese)
Major source of antibiotics (penicillin)

191
Q

Candida albicans is an example of what

A

Fungal infection

192
Q

Midzaoles are an example of what

A

Anti-fungal

193
Q

Midzaoles: examples

A

Miconazole
Ketoconazole
Clotrimazole

194
Q

Midzaoles: used where other than healthcare

A

Used in agriculture to keep seeds and crops from molding

195
Q

What do Midzaoles treat

A

Fungal skin infections

196
Q

Midzaoles: therapeutic effects

A

Improve s/s of athletes foot, jock itch, or ringworm

197
Q

Midzaoles adverse side effects

A

Topical skin irritation

Rash

198
Q

Triazole is what?

A

Anti-fungal medication

199
Q

Triazole examples

A

Fluconazole

200
Q

Triazole treats what

A

Systemic yeast
Oral thrush
Cryptococcal meningitis

201
Q

Triazole administration

A

Oral or IC

202
Q

Triazole side effects

A

Hepatotoxic (increase fluids, monitor for signs of liver failure)

203
Q

Allylamines are what

A

Antifungals

204
Q

Allyamines: examples

A

Terbinafine

205
Q

What does Allyamines treat

A

Athletes foot, jock itch, ringworm

206
Q

Allyamines: administration

A

Topical

Orally for nail fungus

207
Q

Allyamines: therapeutic action

A

Improved s/s of tines infections

208
Q

Allyamines side effects

A

Hepatotoxic

External use only (? Says I can do oral or nail fungus)

209
Q

Polyenes are what

A

Anti-fungals

210
Q

Polyenes: examples

A

Nystatin and amphotericin B

211
Q

Polyenes (Nystatin)

A

Yeast of skin, mouth, vagina

GI fungal infections

212
Q

Polyenes (Nystatin) therapeutic action

A

Improve s/s of yeast infections

213
Q

Polyenes (nystatin) side effects

A

External use only

214
Q

Polyenes administration Nystatin

A

Topically

? Can be used for GI fungal infections, can you take orally?

215
Q

Polyenes: amphotericin B — administration

A

IV

216
Q

Polyenes (Amphotericin B) side effects

A

Ototoxicity
Hypokalemia
Hepatotoxicity
Nephrotoxicity

217
Q

Polyenes (Amphotericin B): things to monitor

A

BUN and creatinine
I&O
LFTs

218
Q

Polyenes (Amphotericin B): BLACK box warning

A

Do not use if fungal disease is noninvasive

— only use if you have to; very hepatotoxic

219
Q

What are examples of anti malarials

A

Chloroquine

Anti-Protozoa

220
Q

Anti-Malarial: therapeutic action

A

Prevention or improvement of acute attack of malaria

Prophylacticly, take for 4 weeks after leaving the area / exposure

221
Q

Anti-Malarial side effects

A

A. Vision changes
B. Ototoxic
C. Nephrotoxic
D. HA, drowsiness, N/V, CV collapse and convulsions (all these are w/ severe toxicity)

222
Q

Anti-Malarial drugs, things to monitor

A

OD
Alcohol use
Hx psoriasis, GI, neurological or blood disorders
AST and ALT

223
Q

Anti-Malarial drugs are contraindicated in who

A

People with retinal or visual field changes

224
Q

Anti-Malarial - with or without food

A

With food

225
Q

Anti-Malaria: why do people not take it consistently

A

Extended length of therapy

226
Q

What are examples of anti-Protozoa drugs

A

Metrogel

Metronidazole IV

227
Q

Metrogel / Metronidazole IV: administration

A

PO
IV
Topical
vaginal

228
Q

Anti-Protozoa drugs (Metrogel / Metronidazole IV): monitor foe what

A

Siezures, peripheral neuropathies, dizziness

229
Q

Anti-Protozoa drugs (Metrogel / Metronidazole IV): side effects

A 
Dry mouth
Dark urine
Siezures
Peripheral neuropathy
Psychotic reactions 
Hepatotoxic
230
Q

Anti-Protozoa drugs (Metrogel / Metronidazole IV): contraindicated ind.

A

Pregnant women

231
Q

Anti-Protozoa drugs (Metrogel / Metronidazole IV) treat what

A

STIs - self and partner need to be treated

— makes sure patient is taking ENTIRE course of medication

232
Q

Anti-Protozoa drugs (Metrogel / Metronidazole IV): special reactions

A

Disulfuram interactions

233
Q

Anti-Helmintic medications are used to treat what

A 
Roundworms = nematoda 
Flatworms = platyhelminthes
234
Q

Anti-Helmintic: example

A

Mebendazole

235
Q

What are special considerations when someone has an helminic infection

A

Wash hands, linens, towels and clothing
Wash food / cook thoroughly
Wear shoes

236
Q

Anti-Helmintic (mebendazole): contraindicated ind.

A

Pregnant women

237
Q

Anti-Helmintic (Mebendazole): therapeutic action

A

Get rid of s/s or worms

238
Q

Anti-Helmintic (Mebendazole): side effects

A

Hepatotoxic

Bone marrow suppression (leave you at risk for other illnesses)

239
Q

Anti-Tuberculars treat what

A

Mycobacterium TB

240
Q

What are examples of Anti-Tuberculars

A

Isoniazid, Rifampin

241
Q

Anti-Tuberculars (isoniazid and rifampin): side effects

A 
Hepatotoxic 
GI upset
Decrease effectiveness of oral contraceptives
Peripheral neuropathy 
Vision changes
Rifampin (orange secretions)
242
Q

Anti-Tuberculars (isoniazid and rifampin): what do you want to avoid

A

Tyramine foods (aged meats, cheeses, wine)

243
Q

Anti-Tuberculars (isoniazid and rifampin): what might you want to add to your diet

A

Vitamin B6

244
Q

Anti-Tuberculars (isoniazid and rifampin): therapeutic goals

A

Negative sputum

Eliminate s/s TB (productive cough, fever, night sweats)

245
Q

Glycopeptides are what

A

Antibacterials

246
Q

Glycopeptide example

A

Vancomycin

247
Q

Glycopeptide (vancomycin) administration

A

IV - poorly absorbed by GI tract
Oral for C. Diff

Avoid rapid administration

248
Q

Glycopeptide (vancomycin) side effects

A

Ototoxic
Red Man Syndrome
Nephrotoxic
Stephen Johnson Syndrome

249
Q

Glycopeptide (Vancomycin): red man syndrome - what is it and what do you do when it happens

A

When administered too fast

  • flushed, red, hot, sweaty
  • must stop infusion
  • call provider
  • administer Benadryl
  • resume at slower rate
  • this is NOT an allergic reaction
250
Q

Glycopeptide (vancomycin): Stephen Johnson syndrome

A

Skin blistering side effect to vancomycin

- very uncommon but it does happen with many anti-infective medications

251
Q

What are things to keep in common with Vancomycin

A

Narrow window for therapeutic index (measure peak and trough)
This is the drug that we treat first line if someone has developed C. Diff

Pharmacology (10 decks)

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