Week 2 McGowan CIS Buzzwords Flashcards
benign hyperpigmentation of the colon
melanosis coli d/t laxative abuse
pseudomembranous colitis
C. diff
villous atrophy
celiac
fecal elastase
chronic pancreatitis d/t pancreatic insufficiency
iron def anemia, dermatitis herpetiformis
celiac disease
bloody diarrhea, undercooked beef
E. coli (EHEC) 0157:H7
what 2 conditions can gastroenteritis cause?
lactase deficiency, or IBS
rectal lactulose
hepatic encephalopathy (confusion due to buildup of ammonia) - causes diarrhea
non-anion gap metabolic acidosis
secretory diarrhea
elevated osmotic gap
osmotic diarrhea
fecal calprotectin
inflammation in GI tract (IBD)
when would you see hyponatremia and hypokalemia?
profuse diarrhea
- weight loss
- diarrhea up at night
- fever
- hematochezia/melena
- acute onset
alarm symptoms
VIPoma
pancreatic cholera (secretory diarrhea)
tea colored urine
cholecystitis
omeprazole is a risk factor for what?
C. diff assoc colitis
malodorous water diarrhea
giardia
- dx: stool antigen
what is a complication and risk factor of toxic megacolon
- caused by C. diff infection and UC
- at risk of perforation (especially when cecum >10cm)
metabolic acidosis or alkalosis associated with diarrhea?
acidosis
primary sclerosing cholangitis is a complication of what?
UC
norovirus associations
cruise ships, child care
- wash hands with SOAP AND WATER
microscopic colitis
medication induced inflammation
what are the risk factors of acute acute ischemic colitis?
- CAD
- vascular disease
- vasoconstrictive drugs
- marathon runners
severe, acute crampy abdominal pain (comes out of nowhere)
- followed by bloody BM
acute ischemic colitis
anti-DGP
test for celiac in IgA def patients (anti-digliadin peptide)
celiac’s have a higher risk of what?
osteoporosis (d/t malabsorption)
PAS stain on biopsy
Whipple disease
stool antigen?
Giardia (common cause!)
when would you order EGD with duodenal biopsy?
Celiac and Whipple
what are the 3 main causes of chronic diarrhea?
- meds
- IBS
- lactose intolerance
40-50 y/o male
- malabsorption (vit A. D, E, K def)
- non acid fast gram positive bacillus (PAS positive)
Whipple disease
elevated iron saturation
hemachromatosis -> YERSINIA
what is threshold Hg level to give blood
give blood if < 7g/dL
fresh frozen plasma (FFP)
helps with clotting!
IV pantoprazole
PPI + EGD
what is the workup for most UGIB?
- start PPI
- do endoscopy (to see what’s going on)
skip lesions
CD
outpouchings in the colon
diverticulosis
painless, profuse hematochezia
- stops on it’s own (no EGD necessary)
diverticulosis
acute, painful cramping, lots of bleeding
acute ischemic colitis
occult bleeding, pencil thin stools
colon cancer
inflammation (leukocytosis), LLQ pain, no blood
diverticulitis
rectal pain, no abd pain, bright red blood on toilet paper
hemorrhoid
malformation of venous system
vascular ectasia
thousands of adenomatous polyps
FAP
gastric adenocarcinoma
Lynch syndrome
MALToma
H. pylori
FAP, juvenile polyps, Peutz-Jegher, Cowden syndrome
hamartomatous polyps
what are the 2 co-morbidities of angioectasia of ascending colon?
- chronic renal failure
- aortic stenosis
can bloody noses cause melena?
yes! can swallow the bloody
will UC cause melena?
probably not
- LGIB -> hematochezia
- smoker
- dysphagia
- GERD
increased risk esophageal cancer
- no dysphagia
- hematochezia (not melena)
colon cancer
what two workups are contraindicated in toxic megacolon?
- colonoscopy
- barium enema
- can cause perforation
- > do plain abd Xray!!
lead pipe sign, loss of Haustra
UC
string sign on plain Xray
CD
increased pressure at LES
achalasia
chelitis, koilonchya, iron def anemia, esophageal webs
Plummer-Vinson syndrome
currant jelly stool
intussusception
- hamartomatous polyps
- hyperpigmentation of lips
Peutz- Jegher syndrome
right side colon cancer, DNA basepair mismatch
- endometrial, ovarian metastases
Lynch syndrome
tx with IV metranidazole
C. diff
- more severe cases get vancomycin PO
tx with oral corticosteroids
IDB
tx for Shiga-like toxin
- +fecal leukocytes (leukocytosis)
rehydration
- EHEC (do NOT give abx! -> HUS)
HPV increases risk of what?
anal cancer
tearing pain with bowel movement, lots of bright red blood
anal fissure
10 years prior to when youngest first-degree relative was diagnosed of colon cancer, or 40
colonoscopy
capsule endoscopy
to view AVM (Crohns)
periumbilical pain “out of proportion” from exam
- NV
- thumb printing on Xray
acute mesenteric ischemic
red whale markings
esophageal varices
aortic stenosis
AVM
mucocutaneous macules on buccal mucosa
Peutz-Jegher syndrome
ankylosing spondylitis “bamboo spine”
UC (HLA-B27)
- erythema nodosum
- pyoderma gangrenosum
- uveitis
- aphthous ulcers
- DVT
- nephroplithiasis
extraintestinal manifestation of IBD
primary sclerosing cholangitis
UC