DSA 6: RUQ and Epigastric Pain Flashcards
what are the 4 main concerns on DDx for RUQ and epigastric pain?
- gallbladder disease
- hepatitis
- pancreatitis
- PUD
positive sign: deep inspiration or cough during palpation of RUX produces increased pain or inspiratory arrest
Murphy’s sign
what are the two major types of gallstones?
- cholesterol (80%)
- calcium bilirubinate (<20%)
what is the best diagnostic tool for cholelithiasis?
- *RUQ ultrasound/hepatobiliary US**
- NOTE: stones seen as “acoustic shadow””
what are the risk factors of gallstones?
- family hx
- female
- fair
- fate
- fertile
- forty
what are the protective factors for gallstones?
- low carb diet
- physical activity
- cardiorespiratory fitness
- consumption of caffeine (in women)
- ligh intake of Mg and polyunsaturated/monosat fat (in men)
- ASA, NSAIDs
calculous gallstones (>90% of cases) impacted in **cystic duct*
- can be acalculous stones
- large fatty meal -> acute attack
- bilirubinemia
- sometime jaundice is present, suggesting choledocolithiasis (bile duct obstruction)
acute cholecystitis
- dx: RUQ abd US
what is a severe complication of acute cholecystitis to keep in mind?
- *emphysematous cholecystitis** (air lining the gallbladder)
- secondary infection with a gas-forming organism
- requires urgent cholecystectomy!
what is the procedure of choice for dx and therapy for choledocolithiasis?
ERCP with sphincterotomy and stone extraction (can be done in same operation)
what is Charcot’s triad?
- RUQ pain
- fever/chills
- jaundice
what is the Reynold pentad? when does it present?
Charcot triad + altered mental status and hypotension
- ascending cholangiitis (infection of biliary tract as result of obstruction, leads to invasion of bacteria from duodenum)
- is very similar to choledocholithiasis, but will have positive blood cultures for E. Coli, Klebsiella, or Enterococcus
what are the top 2 causes of pancreatitis?
- alcoholism
2. gallstones
RUQ pain (similar to biliary colic), nausea, but normal ultrasound of gallbladder (no stones, sludge, microlithiasis, wall thickening or dilation)
biliary dyskinesia
- consider Rome III dx criteria for functional gallbladder
HIDA scan (radionucleotide scan - nuclear medicine Technetium Tc99m) what are normal and abnormal findings?
- normal: gallbladder visualized within 1 hour of injection, tracer also seen in small bowel
- abnormal: GB NOT seen -> stone in cystic duct of cholecystitis
cholecystokinin stimulated hepatobiliary iminodiacetic scan (CCK-HIDA)
- what is considered abnormal and warrants cholecystectomy?
an ejection fraction of less than 35-38% (should be much high with presence of CCK)