Week 2 - Infection Prevention & Control Flashcards
What does HAI stand for?
Health care associated infections
What are HAI?
Infections the patient did not have but picked up at health care
True or false?
1/9 patients admitted to Canadian hospitals acquire an infection as a consequence of their hospital stay
True
- Health care associated infections were the 11th leading cause of death two decades ago
- But are now the fourth leading cause of death for Canadians
What are the factors affecting infection risk?
Age
Nutrition and protein intake
Stress
Chronic disease
Medical therapies/immunosuppression
How does age affect infection risks?
Age
- Infants and older adults at increased risk b/c they don’t have great immunity
How does nutrition & protein intake affect infection risks?
Nutrition and protein intake
- To have the ability to fight off infections
How does stress affect infection risks?
Stress
- Hormones released (cortisone) decrease inflammatory responses; prolonged stress decreases resistance to infection
How does chronic disease affect infection risks?
Chronic disease
- Immune system (leukemia, AIDS)
- Burns
- Open wounds
- Peripheral vascular disease
- Damage of BVs in hands, feet, face, etc
- Emphysema
- Can’t cough & clear things out
- Bronchitis
- Can’t take deep breaths
How does medical therapies/immunosuppression affect infection risks?
Medical therapies/immunosuppression
- Chemotherapy
- Cancer treatment: will also wipe out all fast growing cells in the immune system
- Radiation
- Organ transplants
- Taking medication to suppress immune system to avoid body not getting used to the new organ thus immune system is very weak
- Steroid (anti-inflammatory) therapy
- Surgery
- Can’t take deep breaths
What are defenses against infection?
Immune response protects the body by neutralizing pathogen and repairing damaged body cells
Specific protection against pathogens
- Antibodies
Non-specific protection:
- Normal flora help fight infection and maintain homeostasis
- Body systems defences (eg. skin, saliva, respiratory cilia, gastric acid)
What is an inflammation?
Inflammation: vascular reaction delivers fluid, blood products, nutrients & immune cells to area of tissue injury
What is the cycle of the chain of infection?
Infectious agent
Reservoir
- Right pH, temp
- Most organisms like dark, moist, damp
Portal of exit
- Openings on body
Mode of transmission
- Airborne
- Common vehicle
- Physical contact
Portal of entry
- Similar to portal of exit
Host
- Factors can increase the risk
Give some examples of infectious agent
Microorganisms such as bacteria, viruses, fungi, and protozoa cause infection.
What does the spread of infectious agent depend on?
– Number
– Virulence (ability to cause disease)
– Entry and survival in host
– Susceptibility of host
What is a reservoir?
Place where a pathogen can survive or grow
What are the 6 factors that pathogen requires to be appropriate in order to survive?
Food
Oxygen
Water
Temperature
pH
Minimal light
What is the most common reservoir for a pathogen?
The human body
What does it mean to be colonized? Think in terms of infections
“Colonized”
pathogen is present, does not cause disease
- Common for ppl in health care
- Can still transfer the disease to other ppl
What does it mean to be carriers? Think in terms of infections
“Carriers”
animals or persons who show no symptoms, but disease may be transferable
- carrier of Hepatitis B without the symptoms
What is the portal of exit?
Path away from the reservoir
- Required in order to enter another host
- Natural (eg. mouth, nares) and artificial openings (eg. catheters
What are the 5 ways of transmission?
- Contact: direct & indirect
- Droplet
- Airborne
- Vehicle-common contaminated source
- Vectorborne
Some organisms can be spread in more than one way (chicken pox, influenza)
How does airborne transmission work?
Airborne
- Can float & travel
- Can not control
- Distance does not matter
- eg. chicken pox
How does droplet transmission work?
Droplet
- Wet particles carrying bacteria
- Only go/travel maximum of 6 feets (only heavy enough for 6 feets)
How does contact transmission work?
Contact
- Direct
- Indirect
- Can still be through touch
- Can be a third person (eg. person A transferred to person C then person C gives it to person B)
What are vectorborne transmission?
Through insects or animals
Give some examples of portal of entry
Path into the host
GI tract
Mucous membranes
Respiratory tract
Broken skin
Genitourinary tract
Can all also be portal of exit
What is the meaning of susceptibility?
- Patient’s resistance to the pathogen
What does a patient’s susceptibility depend on?
- Antibiotic resistance
- If a person is immunocompromised
- Age
- Nutrition
- Stress
- Chronic disease
- Medical therapy
- Immunizations and actual contraction of the disease
What are the 2 purposes of infection control?
- Protecting patients from acquiring infections
- Protecting health care workers from becoming infected
How to break the chain of transmission at:
Infectious agent
- Cleaning
- Disinfection
- Sterilization
- Antimicrobial therapy
- Antibiotics cleaning