Week 2- Adaptive Immunity Flashcards

1
Q

Adaptive Immunity is

A

-More Specific
-Has Memory

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2
Q

Innate immunity works with adaptive by

A

introducing tings for adaptive to kill

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3
Q

General characteristics of adaptive:
Recognition of ____ (antigens)

A

non self

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4
Q

General characteristics of adaptive:
I ___ than innate but more ___

A

slower but more specific

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5
Q

General characteristics of adaptive:
Adaptive provides ____ term protection

A

longer

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6
Q

Clonal Diversity begins at birth and occurs primarily in primary____ organs

A

lymphoid

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7
Q

Examples of primary lymphoid organs

A

thymus, bone marrow

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8
Q

As B & T cells mature, they migrate to ____ lymphoid organs

A

secondary

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9
Q

Examples of Secondary lymphoid organs

A

spleen, lymph nodes, adenoids, tonsils, Peyer’s patches (intestines)

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10
Q

Clonal Selection requires

A

exposure of cell to antigen

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11
Q

Clonal selection: Antigen is processed then presented to immune cells by

A

Antigen Presenting Cells (APCs)

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12
Q

B cells turn into

A

Antibodies

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13
Q

T cells turn into

A

Effector Cells

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14
Q

Active immunity

A

-Produced after natural exposure to ANTIGEN
-Body Builds up own antibodies

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15
Q

Passive Immunity

A

Antibodies from somewhere or someone else introduced to body

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16
Q

Examples of Active immunity

A

Infection, Vaccine

17
Q

Examples of Passive Immunity

A

Maternal antibodies, Monoclonal antibodies/IVIG

18
Q

An antigen that can trigger an immune response

A

Immunogenic Antigen

19
Q

Epitope

A

Part of antigen that binds

20
Q

Paratope

A

Part of antibody that binds

21
Q

Immunogenic capability depends on

A

how foreign, size, chemically complex, amount

22
Q

antibody =

A

Immunoglobulin

23
Q

Antibodies/Immunoglobulin are produced by

A

Plasma cells

24
Q

IgG

A

Chronic inflammation/infex

25
Q

IgA

A

Secretory (immune function of mucous membranes)

26
Q

IgM

A

Initial response

27
Q

IgE

A

Allergic response

28
Q

-Most abundant
-Crosses placenta
-Accounts for most of protective activity

A

IgG

29
Q

-Secretory organs
-Mucus, gut secretions
-Located along glands, mucosal surfaces

A

IgA

30
Q

-First responder produced during response to antigen

A

IgM

31
Q

-Defends against parasite
-Allergic reactions
-Histamine release

A

IgE

32
Q

What cells proves antigen from cite of inflammation

A

Dendritic Cells

33
Q

Antigen processing and presentation requires what 3 things

A

1) Appropriate antigen type
2) Lymphocyte recognition
3) Appropriate presentation of antigen

34
Q

When is IgM detectable in body after initial exposure

A

5-7 days (in body before that but not detectable)

35
Q

Superantigens

A

-out of control inflammatory response
–excessive production of cytokines

36
Q

What cells provide peripheral tolerance to antigens
(If we don’t have -> autoimmune, cancer)

A

T regulatory lymphocytes