Week 2- Adaptive Immunity

Question 1

Adaptive Immunity is

Answer 1

-More Specific
-Has Memory

Question 2

Innate immunity works with adaptive by

Answer 2

introducing tings for adaptive to kill

Question 3

General characteristics of adaptive:
Recognition of ____ (antigens)

Answer 3

non self

Question 4

General characteristics of adaptive:
I ___ than innate but more ___

Answer 4

slower but more specific

Question 5

General characteristics of adaptive:
Adaptive provides ____ term protection

Answer 5

longer

Question 6

Clonal Diversity begins at birth and occurs primarily in primary____ organs

Answer 6

lymphoid

Question 7

Examples of primary lymphoid organs

Answer 7

thymus, bone marrow

Question 8

As B & T cells mature, they migrate to ____ lymphoid organs

Answer 8

secondary

Question 9

Examples of Secondary lymphoid organs

Answer 9

spleen, lymph nodes, adenoids, tonsils, Peyer’s patches (intestines)

Question 10

Clonal Selection requires

Answer 10

exposure of cell to antigen

Question 11

Clonal selection: Antigen is processed then presented to immune cells by

Answer 11

Antigen Presenting Cells (APCs)

Question 12

B cells turn into

Answer 12

Antibodies

Question 13

T cells turn into

Answer 13

Effector Cells

Question 14

Active immunity

Answer 14

-Produced after natural exposure to ANTIGEN
-Body Builds up own antibodies

Question 15

Passive Immunity

Answer 15

Antibodies from somewhere or someone else introduced to body

Question 16

Examples of Active immunity

Answer 16

Infection, Vaccine

Question 17

Examples of Passive Immunity

Answer 17

Maternal antibodies, Monoclonal antibodies/IVIG

Question 18

An antigen that can trigger an immune response

Answer 18

Immunogenic Antigen

Question 19

Epitope

Answer 19

Part of antigen that binds

Question 20

Paratope

Answer 20

Part of antibody that binds

Question 21

Immunogenic capability depends on

Answer 21

how foreign, size, chemically complex, amount

Question 22

antibody =

Answer 22

Immunoglobulin

Question 23

Antibodies/Immunoglobulin are produced by

Answer 23

Plasma cells

Question 24

IgG

Answer 24

Chronic inflammation/infex

Question 25

IgA

Answer 25

Secretory (immune function of mucous membranes)

Question 26

IgM

Answer 26

Initial response

Question 27

IgE

Answer 27

Allergic response

Question 28

-Most abundant -Crosses placenta -Accounts for most of protective activity

Answer 28

IgG

Question 29

-Secretory organs -Mucus, gut secretions -Located along glands, mucosal surfaces

Answer 29

IgA

Question 30

-First responder produced during response to antigen

Answer 30

IgM

Question 31

-Defends against parasite -Allergic reactions -Histamine release

Answer 31

IgE

Question 32

What cells proves antigen from cite of inflammation

Answer 32

Dendritic Cells

Question 33

Antigen processing and presentation requires what 3 things

Answer 33

1) Appropriate antigen type 2) Lymphocyte recognition 3) Appropriate presentation of antigen

Question 34

When is IgM detectable in body after initial exposure

Answer 34

5-7 days (in body before that but not detectable)

Question 35

Superantigens

Answer 35

-out of control inflammatory response --excessive production of cytokines

Question 36

What cells provide peripheral tolerance to antigens (If we don't have -> autoimmune, cancer)

Answer 36

T regulatory lymphocytes