WEEK 2 Flashcards
Non-blanching petechial rash
N. Meningitidis
APAP antidote
N. Acetylcysteine
Anticholinergic antidote
Physostigmine
Except TCA’s
Benzo antidote
Flumazenil
Cyanide antidote
Na Nitrite
Methanol antidote
Ethanol
Narcotic antidote
Naloxone
Garlic odor on breath
Acute arsenic ingestion
Dig toxicity causes?
Hyperkalemia
Dig reversal agent
Digabind
Pinpoint pupils and resp depression =
Opiate overdose
3 C’s of TCA tox
Cardiac abnormalities
Convulsions
Coma
EKG abnormalities in TCA tox
Wide QRS
Prolonged QT interval
Early signs of APAP tox
N/V
Rotten ages
NItrogen sulfide
ASA Tox
Resp alkalosis
Met acidosis
Normal pH
7.35 - 7.45
Normal CO2
35 - 45
Normal O2
83 - 102
Normal HCO3
22 - 28
Normal Anion Gap
10 - 16
pH: 7.48
CO2: 40
HCO3: 30
Metabolic Alkalosis
pH: 7.45
Co2: 47
HCO3: 29
Metabolic Alkalosis
with
Respiratory Comp
pH: 7.30
CO2: 40
HCO3: 18
Metabolic Acidosis
Fruity odor to breath
DKA
DKA
*** Aggressive fluid therapy with NS *** .1 units/kg insulin per hour Continuous infusion is preferred Potassium repletion Routine bicarb not recommended
Almost all patients in DKA present with glucose above
300 mg/dL
Most will be above 500
HHNS occurs in
Type 2 diabetics
No ketone production because of enough insulin to use glucose in cells.
HHNS syndrome
Severe hyperglycemia > 600
Hyperosmolarity > 315 mOsm/kg
Relative lack of ketonemia (pH >7.3)
HHNS presentation
Usually elderly
AMS
Non-ambulatory
Concomitant infxn
Glucose less than ___ is generally a concern
About 60
45 is very dangerous
Hypoglycemia Tx
15 - 20g of glucose (nonemergent)
1 g/kg of D50 IV (emergent)
Prescribe glucagon
Adjust insulin therapy
Hypoglycemia accounts for ___% of patient presentations to the ED with AMS
7%
Non-diabetic causes of hypoglycemia
ETOH
Sepsis
Primary adrenal insufficiency
Addisons
Most common cause of adrenal insufficiency
Chronic exogenous steroid use
Darkening of skin in addisons is caused by?
Increased melanocyte stimulating hormone release
Hypotension in adrenal crisis is usually refractory to what tx?
Catecholamine and fluid admin.
Cortisol must be replaced
Where is adrenal crisis seen?
Undiagnosed addisons with serious infxn or acute stress.
Adrenal infxn or hemorrhage
Rarely in 2ndary insufficiency
Adrenal crisis presentation
Hypotension
Abd and flank pain
Pheo rule of 90’s
90% in adrenal medulla
90% unilateral
90% of time not malignant
90% of pts are adults
A positive 24hr Vanillylmandelic acid secretion test =
Pheochromocytoma
Myxedema Coma
Uncompensated hypothyroidism in the elderly.
AMS, hypothermia, brady, hypotension
Myxedema coma often precipitated by ____ exposure
Cold exposure
Myxedema coma tx
Correct hypothermia
IV levothyroxine
Glucocorticoids
Thyroid storm
Severe life-threatening Hyperthyroidism caused by stress, trauma, sepsis
S/S: Fever, arrhythmia, CHF, agitation
Thyroid storm tx
Stabilize, O2, fluids
Beta blockers for HTN
PTU (antithyroid)
Iodine
2nd gen antipsychotics
Olanzapine: Zyprexa
Risperidone (Risperidal)
Ziprasidone: Geodon
FIrst choice for chemical restraints
Haldol and benzos
Lab needed in AIDS encephalopathy
CD4 count
Cocaine w/d tx
Supportive
no meds shown to help
Which paralytic in CI in meth intubation
Succs
What should HTN in meth OD be treated with?
Nitroprusside
Avoid beta blockers
NMS
Neuroleptic malignant syndrome
AMS, muscular rigidity, hyperthermia
Caused by compazine, neuroleptics antipsychotics
When do etoh w/d seizures occur?
12 - 48 hrs after last drink
When does w/d hallucinosis occur
12 - 24 hrs, resolve within 24 - 48
Usually visual
When do DT’s occur?
48 - 95 hrs
Can last 1-5 days
DT tx
Supportive
Benzos
Phenobarb if benzos not working
NO antipsychotics
Does psychosis alone meet legal criteria for involuntary tx?
No
Catatonia
Inability to move normally despite physical ability to do so
Tx with lorazepam
Abx for meningitis
Rocephin IV
Paradoxical crying (cries more when being held) in an infant is indicative of?
Meningitis
DOC for MRSA
Bactrim
Clinda is alternate
Oslers nodes and janeway lesions =
Infectious endocarditis
Imaging for endocarditis
TEE is best
Toxic shock syndrome
Results from the TOXINS absorbed from a localized infxn.
NOT sepsis, but causes by bacterial infections.
Malaria
Caused by plasmodium falciparum
Transmitted b mosquitoes
Sx occur 12 - 35 days after exposure
Botulism
BIlateral cranial neuropathies
symmetric descending weakness
Absence of fever
Smallpox agent
Variola virus
Anthrax agent
Bacillus Anthracis
Is cutaneous anthrax painful?
No, painless
Anthrax tx
Ciprofloxacin or doxy for 2 months
Toxic dose of APAP
> 140 mg/kg
TCA’s are which class
Anticholinergic
Anticholinergic OD saying
Hot as a hare, red a a beet, dry as a bone, blind as a bat and mad as a hatter