Week 13: (A) Coupling and Skeletal Muscle Contraction

Question 1

What are the 3 types of muscle function?

Answer 1

skeletal, cardiac, smooth

Question 2

What is the primary function of the muscle?

Answer 2

generate force of movement in response to physiological stimulus
Transduce chemical or electrical signal to a mechanical response

Question 3

What needs to increase for all muscle types to contract?

Answer 3

increase [Ca2+]i

Question 4

What muscle type will we focus on?

Answer 4

skeletal

Question 5

What does skeletal muscle contract in response to?

Answer 5

neuromuscular synaptic transmission

Question 6

How many NMJ does a skeletal muscle fibre have?

Answer 6

1 - single

Question 7

What receptors are on skeletal muscle post synaptic neurone?

Answer 7

nAChR

Question 8

What inactivates ACh

Answer 8

AChE

Question 9

What 3 main structures make up a skeletal muscle

Answer 9

Epimysium, perimysium, endomysium

Question 10

What is the location of a muscle fibres in the muscle?

Answer 10

There are many muscle fibres in each fascicle surrounded by an endomysium

Question 11

What does the muscle fibre contain?

Answer 11

“sacs” called myofibrils

Question 12

What do myofibrils contain?

Answer 12

myosin and actin

Question 13

What is the endomysium?

Answer 13

surround each and every muscle fibre

Question 14

What 2 bands does myosin have?

Answer 14

I band & A band

Question 15

What is the light band?

Answer 15

I band

Question 16

What is the dark band?

Answer 16

A band

Question 17

What filaments are in the A band?

Answer 17

myosin & actin

Question 18

What is the thick filament in A band?

Answer 18

myosin

Question 19

What is the light filament in A band?

Answer 19

actin

Question 20

what defines the sarcomere?

Answer 20

smallest component of a muscle that can contract

Question 21

Where is the M line located?

Answer 21

down the centre of the sarcomere

Question 22

What band is on either side of the sarcomere?

Answer 22

Z line, I band

Question 23

What filament surrounds the thick filament?

Answer 23

thin filament (actin)

Question 24

What is the gap of muscle next to the A band in the sarcomere?

Answer 24

I band (light)

Question 25

What line runs in between of the A and I bands?

Answer 25

Z line

Question 26

what filament is surrounded by thin filament?

Answer 26

thick filament (myosin)

Question 27

What line connects 2 actin filaments of sarcomeres?

Answer 27

Z line