week 12: cancer Flashcards

1
Q

leukaemia is a

A

clinal malignant disorder causing increased dysfunctional cells and loss of cell division regulation

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2
Q

acute leukaemia

A

undifferentiated or immature cells
abrupt and rapid onset
short survival time

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3
Q

chronic leukaemia

A

predominant cell looks mature but doesn’t function properly

longer survival time

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4
Q

acute leukaemia early cm

A

fatigue, bleeding, fever

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5
Q

acute leukaemia neuro manifestations

A

headache, facial palsy, blurred vision, meningeal irritation

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6
Q

acute leukaemia tx

A

chemo, blood transfusions, abx, anti fungals, antivirals, bone marrow transplant

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7
Q

chronic leukaemia symptoms

A

extreme fatigue
weight loss
night sweats
low grade fever

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8
Q

marker for CML

A

philadelphia chromosome

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9
Q

CLL involves malignant transformation

A

if B cells

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10
Q

chronic leukaemia tx

A

no cure - bone marrow transplant for survival time

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11
Q

a pap smear is

A

exfoliating cytology

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12
Q

biopsy

A

removal of tissue specimen for microscopic study

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13
Q

tumour markers may be

A
hormones
enzymes
genes
antigens
antibodies
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14
Q

hCG

A

gestational trophoblastic tumours

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15
Q

PSA and PAP

A

prostate cancer

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16
Q

CA125

A

ovarian cancer

17
Q

3 types of lymphoma

A

B cells
T cells
Hodgkin disease

18
Q

HD is distinguished from others by presence of

A

Reed stern berg cells

19
Q

s&s of HD

A

intermittent fever
drenching night sweats
weight loss

20
Q

HD I dx

A

1 lymph node or region

21
Q

HD II dx

A

involves two or more nodes or regions on the same side of the diaphragm

22
Q

HD III dx

A

involved lymph node regions or structures on both sides of the diaphragm

23
Q

HD IV dx

A

involved extranodal sites

24
Q

HD can be dx through

A

CXR and biopsy

25
Q

non hodgkin lymphoma

A

malignant transformation of lymphoid system not characterized by reed stern berg cells

26
Q

non hodgkins normally manifests itself as

A

local lymphadenopathy

27
Q

non hodgkins tx

A

stem cell transplantation