week 12 Flashcards
What does schizophrenia mean?
Splitting of psychic functions. Refers to the breakdown of integration of emotion, thought and action.
Name the three categories of symptoms for schizophrenia
Positive: paranoia/delusions, hallucinations
Negative: Loss/decrease in speech, reduced ability to express emotions.
Disorganised: Incohreant thought/speech, bizarre behaviour, inappropriate affect. only need 2 to be present in 1 month for a diagnosis.
Schzio and genes
Right, so there is a genetic link and there are a few chromosones we have our eye on. But, itll be a crazy mix.
So, how does schizo happen?
Current theory is someone has to have the right sets of chromosones to be suseptible, and then have an incident happen to active the genes (like trauma, illlness, infections, isolation etc).
What drugs are used to treat schizo?
Chlorpromazine: invented by accident, orks fr schizophrenics by calming them down. Gives parkinson like side effects, contibuting to the idea schizophrenia could possible be caused by exccesive dopamine. binds to D1 and D2 receptors. Not perfect, doesn’t work for weeks.
dopamine theory of schizo
spurred by parkinsons/chlorpromazine link, shrinks reckon schizo might happen because they have too much dopamine, which the meds then decrease giving the shakes. Not a perfect system though, like antipsychotics work on synapses fast, so why do they take weeks to kick in.
Depression
A normal reaction to loss, becoming abnormal when it persists or has no cause.
Mania
Overconfidence, reduced need for sleep, impulsivity, more talkative, high energy etc.
Affective disorders:
Psychiatric disorders categorized by disturbances of mood or emotion, AKA mood disorders. depression and mania are part of this.
Depressive disorder
MDD, presistant depressive disorder, bipolar.
What can make someone have an affective disorder
Stresfful experiences (esp. early life trauma), seasonal affective disorder
Monoamine Oxidase Inhibitors (MAOIs)
used to be used as an antidepressant, prevent breakdown of monoamines. pretty unsafe.
Selective monoamine reuptake inhibitors
SSRI’s: prozac, zoloft, paxil. No more effective then tricyclics, but better with side effects.
Lithium
mood stabaliser for BD, but don’t really know why haha lol
How effective are antidepressants really?
MAOIs, SSRIs only work for about 20% of people who take them, and even then they only seem to really work for REALLY depressed people.