week 11, ethics I Flashcards
what is informed consent?
4
voluntary participation to a study
no coercion
no undue incentive
right to withdraw
history of why nuremberg code was created
nazis performed inhumane experiments in the name of science (hypothermia, max altitude before death)
researchers tried to balance between rights, welfare of humans and scientific discovery
what happened during nuremberg trials (1945-1946)
23 nazi doctors were charged with crimes against humanity
what is the nuremberg code (6)
- voluntary, informed consent
2.withdraw at anytime
3.benefits exceed the risks
4.risks must be minimized
5.experimenters must asses risks continously
6.experimenters must be competent
what happened with the Holmesburg prison experiments?
dermatologists tests on black men, they received minimal info about side effects, hiiiigh cash rewards,
what happened with the Tuskegee Syphilis study?
gave black men (only) syphilis with no cure. even though penecilin was discovered which can cure it
what is the belmont report? 3
- respect for persons: protecting autonomy of all people, allows informed consent, researchers must be truthful.
- Beneficence: philosophy of “do no harm”, maximizing benefits and minimizing risks
- justice: non exploitative of communities, fair distribution of costs and benefits
what happened in little albert experiment
goal was to study possibility of conditioning emotions
exposed 9 month old baby to fear conditioning (furry rabbit)
no effort to undo the conditioning
what belmont report rule does the little albert experiment violate?
beneficence, do no harm
why is it important for researchers to ensure the procedure ethical?
power dynamics !! many communities could be exploited
what is the OHRP
office for human research protections, protects rights and welfare of human beings
the OHRP has has branched off to different fields, such as:
APA, AMA, AAA
Guidelines for the protection of the rights of human subjects (built on nuremberg code and belmont report)
- investigator has responsibility to carefully evaluate experiments ethical acceptability
- investigators must obtain approval form institutional review board (IRB)
what does the IRB do?
evaluate risks of the research, if there are, you must ensure the benefits outweigh the risks