Week 11 Flashcards
What is the most prevalent psychotic disorders?
schizophrenia
Schizophrenia has major disturbances in:
thought, emotion, behaviour, and interpersonal relationships.
There has to be one symptoms from these categories to say they have schizophrenia:
- delusions
- hallucinations
- disorganised speech
- disorganised motor behaviour
- negative symptoms (diminished motivation of emotional expression)
Positive symptoms of schizo have been linked to ___
excess of dopamine in the mesolimbic pathway
The negative symptoms of shizophrenia have been associated with a shortage of dopamine in the
mesocortical pathway
What are the more recent antipsychotic that has been developed?
atypical D, partial agonist antipsychotic. Leads to normalising both the mesolimbic and the mesocortical pathway.
Glutamate (NMDA) is now being implicated in:
schizophrenia
What enlarges in schizophrenia in the brain?
ventricular enlargement
TRS may have ___ than general schizophrenia.
a different pathology altogether
What may schizophrenia be related to?
The pruning of excitatory pathways.
Amphetamines may lead to:
induced psychosis
Other systems which may be involved in schizophrenia are
- dopamine
- glutamate
- GABA
- serotonin
- acetycholine
Inflammation might also be involved in
schizophrenia
The makeup and function of the gut is increasingly being linked to:
neurological disorders, including schizophrenia, depression and biopolar disorder.
Adolescent Cannabis users increased their likelihood by ___ of developing schizophrenia
3 fold
