Week 10 - Caffeine Flashcards
What is caffeine
1,3,7-trimethylxanthine (metabolised in the liver)
Removed from WADA list 2004
Commonly used drug
Describe the bio-availability of caffeine
Peak blood caffeine concentrations typically occur 60mins after ingestion in a dose-dependent manner
Benefits could occur soon after intake
Caffeine interacts with all body cells and crosses the blood-brain barrier
What are the effects of caffeine consumption
- Improved vigilance and alertness
- Reduced perception of effort
- Reduced fatigue and pain
Therefore improved performance
What are the proposed mechanisms in how caffeine works
- Muscle ion effect: Caffeine increases the release of intracellular calcium, responsible for muscle contraction
- Metabolic effect: Caffeine increases fat oxidation with possible carbohydrate sparing
- Central effect: - Caffeine can prevent adenosine to bind to its receptors in the CNS, reducing sensations of tiredness and perception of effort (main mechanism)
How does the main mechanism of Caffeine work
Caffeine can stop adenosine from binding to its receptors in the brain, reducing the sensations of both tiredness and pain
How does caffeine content vary across different sources
The caffeine content varies in different sources and can even vary within the same source depending on how it was prepared
What is an advantage to using caffeinated gum
Caffeinated gum can increased absorption and decrease GI distress
What is the optimal dose of caffeine when enhancing athletic performance
Optimal dose is 3mg/kg body weight
What is the recommended timing for consuming caffeine for an event
40-60mins before event
Throughout the event at lower dosages (1.5/mg/kg)
Late during event or before important stage (100-200mg)
What is the effect of caffeine habitual consumption
Caffeine habitual consumption does not affect ergogenic effects, only when high doses are consumed is when performance can be enhanced (6mg/kg/BM)
What would make caffeine more effective in performance
Co-ingestion with CHO is ergogenic and offers greater performance improvements than CHO alone. Ingesting caffeine in drinks contributes to hydration as well
When should caffeine usage be considered
- Endurance sports (>60mins)
- Brief sustained high-intensity sports (1-60mins)
- Team and intermittent sports
- Single efforts involving strength or power
- Pre-training energy boost
What are some risks of caffeine consumption
- Caffeine can affect sleep onset and quality
- Minimal effects on urine losses or overall hydration
- At moderate & high doses, side effects including anxiety, insomnia, inability to focus, GI unrest, irritability
- Dependency to caffeine
What are some safety issues and considerations around caffeine consumption
- Caffeine is considered safe to consume in low to moderate doses (<400mg/day) and <200mg at any one time from all sources. (Unless pregnant)
- Pure or highly concentrated caffeine can be potentially lethal
- Children are suggested to limit caffeine intake (<2.5mg/kg/d)
- Athletes should aim to only use batch-tested supplements
What are some recommendations to caffeine consumption
- Ergogenic effects of caffeine are supported by scientific research
- Can enhance performance in range of different sports
- High doses can cause negative side effects
- Generally safe to use, although varies across individuals
- Practical considerations before consumption would include dosage, timing, product, event