Week 1 Tuesday - Downing - Histology of Skin Flashcards

1
Q

Sebaceous gland

A

Oily gland of the skin (usually of the hair folicle).

  • Holocrine secretion
  • Causes acne
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2
Q

Meissner’s corpuscle

A

Nerve ending in the superficial part of the dermis sensitive to light mechanical touch.

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3
Q

Pacinian corpuscle

A

Nerve ending in the deep dermis sensitive to pressure.

It’s big and round, like PAC-man

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4
Q

Lamellar bodies

A

Contain lipids. Secreted from a granular cell superficially. Form a lipid coat (water barrier).

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5
Q

Keratohyaline granules

A

Present once an epithelial cell enters the Stratum granulosum stage. Eventually these consolidate into a fibrous amorphous mass when the cell enters the Stratum Corneum.

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6
Q

Psoriasis

A

Increase in # of proliferating cells in Stratum basale, increase in cell turnover.

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7
Q

Papillae

A

Secondary dermal ridges; exist in epithelial tissues subject to stress e.g. palms.

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8
Q

Where do melanin granules come from and how do they mature?

A

Golgi of melanocyte, are matured via tyrosinase activity, which is active in the first two steps of the following reaction:

tyrosine peptide -> dopa peptide -> [indole 5,6 quinone]n -> Melanin polymer

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9
Q

Rete cutaneum (cutaneous plexus)

A

Supply of veins and arteries in the reticular (deep) layer of the dermis.

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10
Q

Rete subpapillare (subpapilary plexus)

A

Supply of veins and arteries in the papilary (superficial) layer of the dermis. (sometimes just referred to as the papilary plexus).

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11
Q

Arteriovenous anastomoses

A

(AV shunts) Shunts that allow blood flow to bypass the papilary plexus.
Thermoregulated; open when cold, closed when hot.

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12
Q

This muscle stands hair ‘on end’ and moves sebaceous gland products. What is it and where is it anchored?

A

Arrector pili muscle. Bundle of smooth muscle that in innervated sympathetically. Anchored from the hair follicle sheath to the papillary layer of the dermis.

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13
Q

Lanugo, vellus, and terminal hair

A

Lanugo - Newborn hair
Vellus - fine hair that covers most of the body
Terminal hair - rougher hair (pubic hair, facial hair)

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14
Q

This tissue is located superficially to finger nail root.

A

Eponychium.

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15
Q

This tissue is located under the tip of the fingernail.

A

Hyponychium.

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16
Q

This is the light crescent on the most proximal part of the finger/toe nail.

17
Q

Eccrine sweat glands

A

Major sweat glands of the body, active when working out. Sympathetic innervation.

18
Q

Apocrine sweat glands

A

Sweat glands restricted to the axilla; areolae, and anogenital locations. Activated when nervous. Odorless secretion becomes odored when acted on by bacteria. Sympathetic innervation.

19
Q

Peritrichial nerve endings

A

They allow feel for when a hair is touched.