week 1: intro to the company Flashcards
Novomagic and falcon
key differentiators compared to competitors
Novomagic:
faster for clients
gets more meaningful insights from data available
Who Are We?
Novogene is one of the largest sequencing providers globally, offering multiple platforms and pipelines to accommodate your research needs
We have major presence worldwide in a wide variety of sectors including
- Academics
- Clinical
- Biotech
- Pharmaceutical
- Government
Global presence with labs in the US, China, Singapore, Japan, and Europe
Timeline
Founded 2011, Beijing
2014 - HQ in US & UK
2016 - opened first US Sequencing center at UC Davis
2018 - Sequencing Center at Cambridge, UK established
2019 - HQ Netherlands & Japan established
2020 - sequencing center in Singapore established
2020 - launched our fully automated NGS platform, Falcon
Novogene services portfolio
Genome Sequencing
- Human WGS
- Animal/Plant WGS
- Microbial WGS
- Target Region Sequencing
- Human/Mouse Whole Exome
- Clinical Whole Exome (CLIA/CAP)
- De Novo (Animal/Plant/Microbial) Sequencing
Transcriptome
- mRNA-Seq
- Non-coding RNA Seq (long non-coding, smallRNA, circRNA)
- Isoform Sequencing
- Single-Cell RNA-Seq
- Prokaryotic RNA-Seq
- Metatranscriptome
- FFPE RNA-Seq
Epigenome
- Whole Genome Bisulfite (WGBS)
- Reduced Representation Bisulfite (RRBS)
- ATAC-Seq
- ChIP-Seq
- RIP-Seq
Metagenome
- 16S / 18S / ITS Amplicon Sequencing
- Shotgun Metagenomics
Premade libraries
- Full Lane Sequencing
- Full Flow Cell Sequencing
- Partial Lane Sequencing
platforms we offer - short reads
Illumina
- NovaSeq X Plus
- Latest platform released by Illumina, that went live early May 2023 at Novogene
NovaSeq 6000
HiSeq X/4000
MiSeq
NextSeq
platforms we offer - long reads
PacBio
Revio
- Newest sequencer produced by PB, with ~4X the output per SMRT cell (relative to past generation) and faster TAT
Sequel II/Sequel IIe
Nanopore
- PromethION
Illumina (Coming Soon)
- Infinity
single cell offerings - San Jose Lab
10X scRNA-Seq (3’)
parse biosciences
data analysis on high performance computing platform
DELL computing nodes
memory size: 410 TB
computing power: 1727 T flops
storage: 62 PB
automation - falcon
The first fully optimized and automated NGS platform in the industry that allows for significant improvements in efficiency, reliability, & quality for all NGS projects
Designed to remove errors and quality control issues present with manual labor
Single robotic arm completes workflow from start to finish
Allows for 24/7 uninterrupted processes from sample extraction, QC, Library Preparation, Sequencing, to analysis
automation - falcon
falcon allows for a much greater scaling. while achieving an average 60%-time savings, compared to traditional methods
Because of full automation and the ability to analyze and differentiate samples without human intervention, there is extremely high reliability, consistency, & stability end-to-end
traditional methods
- 16 days form library preparation to data release for 500 samples
falcon automation
- up to 90 hours for 500 samples
Automation - Falcon II
Our Second-Generation Platform we currently use in our UC Davis sequencing center
Maintains all the features of Falcon I in a much more compact and flexible platform such as:
- 24/7/365 continuous operation
- 99.99% consistency and reproducibility among all samples Falcon II processes
- Real-time tracking and remote monitoring with unique tracking codes for each sample
- Able to fully process 384 samples a day
Customer Service System (CSS)
real-time project update
- view and track status of your project live 24/7 - from sample pickup to data release
access your genomic
- secured cloud access to your sequencing data
online collaborative tool
- shared functions to manage project/s with lab members and collaborators via ‘my team’
enjoy free visualisation and data analysis tools
cloud-based bioinformatics platform - novomagic
Benefits of Novogene’s Services
High Capacity of Automation
- Falcon I/II are proprietary systems of Novogene, that allow us to process greater number of samples, at faster speeds, relative to other automation platforms
Flexibility in Submissions
- For our full-service projects and full lane sequencing, all pricing is per sample/per lane – you do not have to worry about submitting ‘X’ # of samples per batch to obtain a competitive rate
Guaranteed Data Output per Sample
- Due to the nature of sequencing, although a lane will produce (generally) the expected # of reads, the number of reads per individual sample on that lane may vary slightly. If a sample falls below the # of reads you requested, Novogene will put it back on the sequencer, at no-cost
department break down
sales - build relationship, initial spear head for the clients
TS - more niche projects and takes over science questions. Good quotes, pricing and if they want to move forward
build a contract and know when to get samples
samples get to PC, lots of pressure on them so make sure that they get all the info. that they need. PC team is imperative to us!
make sure there is a PO on file
PC may reach out and get the help of the sales team
PC works with the lab directly to make sure the samples are going well. Lab does not contact sales directly. The ppl in the lab are called the Davis lab - QC team, Seq team, library prep team
sales job is to get clarity on the samples
